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机构地区:[1]滨州医学院,山东烟台264003 [2]广东省中医院,广州510120
出 处:《中国中医基础医学杂志》2016年第9期1208-1211,共4页JOURNAL OF BASIC CHINESE MEDICINE
基 金:广东省中医药局科研课题(2010156)-李丽芸教授经验方调节PCOS患者子宫内膜容受性的临床研究
摘 要:目的:探讨参芪胶囊对改善多囊卵巢综合征患者促排卵周期子宫内膜容受性的临床疗效。方法:将46例多囊卵巢综合征患者按随机数字表法分为对照组与治疗组各23例,对照组采用克罗米芬治疗,治疗组在对照组的基础上加用参芪胶囊治疗。比较2组患者临床疗效、排卵率及妊娠率、子宫内膜厚度及类型、子宫动脉及卵巢间质动脉的血流动力学参数等。结果:治疗组治疗后子宫动脉、卵巢间质动脉RI及PI值均显著降低,治疗前后比较差异有统计学意义;治疗后治疗组左卵巢间质动脉PI、RI也较对照组显著降低,差异有统计学意义,治疗组的子宫内膜厚度明显高于对照组,治疗组妊娠率明显高于对照组。结论:参芪胶囊有改善子宫内膜厚度、子宫动脉及卵巢间质动脉血流的作用,从而改善子宫内膜容受性,提高妊娠率。Objective : To explore the effect of Shenqi Capsule therapy ovulation stimulation cycles on the endometrial receptivity of polycystic ovarian syndrome patients. Methods: 46 patients with polycystic ovarian syndrome were selected and randomly divided into control group and treatment group,23 cases in each group. The control group was treated by Clomiphene,the treatment group added Shenqi Capsule on the basis of the control group. The clinical efficacy,the ovulation rate and pregnancy rate,the endometrial thickness and endometrial pattern,blood flow parameters of uterine artery and ovarian stromal artery of two groups were compared. Results: After treatment,resistive index( RI) and pulsatility index( PI) of the uterine artery and ovarian stromal artery of treatment group were significantly lower,the differences before and after treatment were significant. After treatment,resistive index( RI) and pulsatility index( PI) of the left ovarian stromal artery of the treatment group were significantly lower than the control group. The thickness of endometrium of treatment group was statistically significantly thicker than that of the control group,the pregnancy rate of the treatment group was significantly higher than that of the control group. Conclusion: Shenqi Capsule is effective in improving endometrial thickness,blood flow on the uterine artery and ovarian stromal artery,improving endometrial receptivity of polycystic ovarian syndrome,getting a better pregnancy rate.
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