广西壮族自治区老年艾滋病患者中医证候特点  

Features of Syndrome Patterns of Chinese Medicine in Elderly AIDS Patients in Guangxi Zhuang Autonomous Region

作　　者：姜枫[1] 张荣欣[1] 张亚萍[1] 刘振威[1] 李璇[1] 吴卫群[1] 文彬[1] 邓鑫[1] 

机构地区：[1]广西中医药大学附属瑞康医院艾滋病研究中心,南宁530011

出　　处：《中国中西医结合杂志》2016年第10期1175-1179,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金资助项目(No.81460716);广西自然科学基金资助项目(No.2013GXNSFAA019123);广西中医药民族医药传承创新专项(No.GZLC14-09);广西中医药科技专项(No.GZPT13-18);广西医疗卫生适宜技术研究与开发项目(No.S201308-02);广西科技攻关项目(桂科攻1140003B-62);广西八桂学者及其科研创新团队;广西中西医结合人才小高地

摘　　要：目的采用病例对照的方法研究广西壮族自治区老年艾滋病(human immunodeficiency virus/acquired immune deficiency syndrome,HIV/AIDS)患者的中医证候特点。方法按照病例对照研究方法设计调查表,于2013年10月—2014年4月在广西壮族自治区HIV/AIDS患者集中的地市中抽取定点医疗机构,收集年龄在50岁以上老年HIV/AIDS患者及年龄、性别匹配的体检对照人群的中医证候信息,采用《WF-Ⅲ中医(辅助)诊疗系统》进行证素分析,比较老年HIV/AIDS患者和对照人群的中医病位、病性证素差异,总结老年HIV/AIDS患者的中医证候特点。结果共调查HIV/AIDS患者417例,对照组体检者362名。老年HIV/AIDS患者中医证素分析中病性证素成立的有气虚、阳虚、阴虚、血虚、湿、痰,病位证素成立的有肾、肺、脾、肝。与对照组比较,HIV/AIDS患者成立的病位、病性证素差异均有统计学意义(P<0.05)。结论老年HIV/AIDS患者的证候特点为肾、肺、脾、肝等脏腑的气血阴阳虚损和湿痰等邪内生,中医证候属虚实夹杂、以虚为主。Objective To observe the features of syndrome patterns of Chinese medicine（ CM） in elderly human immunodeficiency virus / acquired immune deficiency syndrome（ HIV / AIDS） patients in Guangxi Zhuang Autonomous Region. Methods According to a case-control study,a clinical questionnaire was designated in elderly HIV / AIDS patients older than 50 years and healthy examinees with age and sex match. Their syndrome information of CM were collected from designated medical institutions in Guangxi Zhuang Autonomous Region from October2013 to April 2014. Analyses of syndrome factors were conducted using WF-ⅢA Diagnosis and Treatment System of Traditional Chinese Medicine（ Auxiliary）. The disease location of CM and nature of diseases were compared between elderly HIV / AIDS patients and the controls. The features of syndrome patterns of CM in elderly HIV / AIDS patients were summarized. Results A total of 417 elderly HIV / AIDS patients and 362 examinees were enrolled. In elderly patients with HIV / AIDS,established syndrome factors of disease nature were qi deficiency,yang deficiency,yin deficiency,blood deficiency,dampness,and phlegm,and established syndrome factors of disease location included Shen,Fei,Pi,and Gan. There were statistical differences in established syndrome factors of disease location or nature between elderly patients with HIV / AIDS and the controls（P〈0. 05）. Conclusions Elderly HIV / AIDS patients were characterized by deficiency of qi,yang,yin,and blood in Shen,Fei,Pi,and Gan,as well as endogenous production of pathogenic factors such as dampness and phlegm. Intermingled deficiency and excess was dominated in elderly HIV / AIDS patients,and mainly manifested as deficiency syndrome.

关 键 词：艾滋病 老年 中医证候 病例对照研究 广西壮族自治区 

分 类 号：R259[医药卫生—中西医结合]