屈螺酮炔雌醇用于预防人工流产术后并发症的临床观察  

Clinical observation of Drospirenone and Ethinylestradiol Tablets for preventing postoperative complications of induced abortion

作　　者：吴鹏[1] 王秀芳[1] 

机构地区：[1]浙江萧山医院妇科,浙江杭州311200

出　　处：《中国生化药物杂志》2016年第8期74-75,共2页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的观察屈螺酮炔雌醇片预防人工流产患者术后并发症的临床疗效。方法选取2015年11月~2016年5月浙江萧山医院妇科门诊实施人工流产的400例患者,按数字随机法分为观察组和对照组,各200例。对照组术后采取常规抗生素止血药物治疗。观察组在对照组基础上给予口服屈螺酮炔雌醇片,每晚1片,21d为1个疗程,连续服用6个疗程。比较2组患者术后并发症盆腔感染、宫腔粘连、再次妊娠、周期性腹痛及2组术后月经恢复时间、阴道出血、子宫内膜厚度情况。结果观察组术后盆腔感染、宫腔粘连、再次妊娠、周期性腹痛的发生率分别为1.5%、0.5%、0.0%、1.5%,明显低于对照组7.0%、3.5%、4.0%、5.5%（P〈0.05）;观察组术后月经恢复时间、阴道出血时间、子宫内膜厚分别为（27.2±1.7）d,（6.2±1.4）d,（7.2±2.3）mm,均低于对照组（32.5±6.0）d,（7.8±2.7）d,（5.0±2.4）mm,2组各项比较差异有统计学意义（P〈0.05）。结论人工流产术后服用屈螺酮炔雌醇片可有效降低并发症的发生,提高患者生活质量。Objective To observe the clinical effect of postoperative complications in patients with induced abortion by taking Drospirenone and Ethinylestradiol Tablets. Methods 400 patients with induced abortion from November 2015 to May 2016 were randomly divided into the observation group and the control group,200 cases in each group. The control group was treated with routine antibiotic therapy. The observation group treatment with Drospirenone and Ethinylestradiol Tablets based on the control group,1 per one night,21 d for a course of treatment,continuous use of 6courses. Compared the 2 groups of patients with postoperative complications of pelvic infection,intrauterine adhesions,pregnancy,recurrent abdominal pain and two groups of postoperative recovery time of menstruation,vaginal bleeding,endometrial thickness. Results In the observation group after pelvic infection,uterine cavity adhesion,pregnancy,periodic abdominal pain incidence were 1. 5%,0. 5%,0. 0%,1. 5%,were significantly lower than that of the control group7. 0%,3. 5%,4. 0%,5. 5%（ p〈0. 05）; the observation group after menstruation recovery time,vaginal bleeding,endometrial thickness respectively（ 27. 2 ± 1. 7） d,（ 6. 2 ± 1. 4） d,（ 7. 2 ± 2. 3） mm,were lower than the control group（ 32. 5 ± 6. 0） d,（ 7. 8 ± 2. 7） d,（ 5. 0 ± 2. 4） mm,two groups of the difference was statistically significant（ p〈0. 05）. Conclusion After artificial abortion,taking Drospirenone and Ethinylestradiol Tablets can effectively reduce the incidence of complications,improve the quality of life of patients,the method is simple,safe,effective and good compliance.

关 键 词：屈螺酮炔雌醇片 人工流产 术后并发症 

分 类 号：R714.2[医药卫生—妇产科学]