乳腺良恶性病变的影像学特征（英文）  

Radiological features of breast malignant and benign lesions

作　　者：车琳琳[1] 翟代庆[1] 鲁雯[1] 刘林祥[1] 于广会[1] 蔡小涛[1] 傅斌[1] 张光玉[1] 

机构地区：[1]泰山医学院放射学院,山东泰安271016

出　　处：《中国医学物理学杂志》2016年第10期973-981,共9页Chinese Journal of Medical Physics

基　　金：Supported by Natural Science Foundation of Shandong Province(ZR2015HL095);Science and Technology Development Plan of Tan'an City(2015NS2159);Taishan Medical University Doctor Foundation(20072009)~~

摘　　要：为了比较乳腺恶性和良性病变在数字化乳腺X线图像中的影像学特征,在美国南佛罗里达大学的数字化乳腺X线图像数据库中随机选取466名病人的数字化乳房X线图像。在乳腺成像领域有着5年以上经验的放射学专家对乳腺恶性和良性病变的影像学特征进行比较。两样本t检验表明恶性乳腺病变在1 cm×1 cm区域内的钙化数量明显高于良性乳腺病变(P<0.001)。同时,恶性乳腺病变中的不规则或有毛刺状边缘的分叶状肿块的比例明显高于良性乳腺病变(P<0.000 1)。而不规则或边缘局限的分叶状肿块的比较结果却截然相反。此外,良性乳腺病变中边缘局限的椭圆或圆形肿块的比例明显高于恶性乳腺病变(P=0.001)。然而,当前研究数据表明只有恶性乳腺病变表现出边缘局限的椭圆或圆形肿块。恶性乳腺病变的结构扭曲率(5.2%)略高于良性乳腺病变(1.7%)(P=0.042)。其他的影像学特征并没有明显差异。本研究表明恶性乳腺病变的主要影像学特征为有毛刺状边缘或者结构扭曲的肿块、钙化集中(在1 cm×1 cm区域内的钙化数量超过21个),而良性乳腺病变的主要影像学特征为边缘局限的肿块。To compare radiological features of breast malignant and benign lesions in digitized mammograms. Digitized mammograms of 466 patients were randomly selected from Digital Database for Screening Mammography, University of South Florida. Radiological features of breast malignant and benign lesions were compared by specialized radiologists who had at least 5 years of experience in breast imaging. Two-sample t test revealed that the number of calcification in an area of 1 cm×1 cm was significantly larger in malignant mammograms than that in benign mammograms （P〈0.001）. The irregular or lobulated mass with spiculated margins rate was significantly higher in malignant mammograms than that in benign mammograms （P〈0.000 1）. An opposite result was found for the irregular or lobulated mass with circumscribed margins. Additionally, the oval or round mass with circumscribed margins presented a significantly higher rate in benign mammograms than that in malignant mammograms （P=-0.001）. However, the present data revealed that only the malignant marnmograms exhibited the oval or round mass with spiculated margins. Architectural distortion rate was slight higher in malignant mammograms （5.2%） than that in benign mammograms （1.7%） （P=0.042）. No significant difference was found in other radiological features. The findings in the study suggest that masses with spiculated margins or architectural distortion, and calcification cluster that the calcification number was more than 21 in an area of 1cm× 1 cm were predominant radiological features in malignant mammograms, while masses with circumscribed margins were predominant radiological features in benign mammograms.

关 键 词：乳腺 病变 数字化乳腺X线图像 钙化 乳腺良性病变X线图像 乳腺恶性病变X线图像 

分 类 号：R814[医药卫生—影像医学与核医学]