妊娠期补钙的临床观察  

Clinical observation of calcium supplementation during pregnancy

作　　者：胡京苗[1] 

机构地区：[1]北京市海淀区妇幼保健院妇产科,100080

出　　处：《中国综合临床》2016年第9期837-840,共4页Clinical Medicine of China

摘　　要：目的：探讨孕期补充钙剂对临床症状、妊娠期高血压疾病发病率及分娩产程的影响。方法选择在我院定期产检、同一季节、相同孕周的孕妇，年龄20-35岁，应用数字表随机分为两组，补钙组220例于孕20周开始每日服用600 mg钙至分娩，对照组192例未补充钙剂或者补钙但不规律或用量未达标准，分别于孕20周和孕36-40周检测血清钙，观察孕期缺钙症状、妊娠期高血压疾病发病率及妊娠的终止方式和产程时间。结果补钙组腰骶痛发生率为21．4％（47／220），腓肠肌痉挛发生率为6．8％（15／220），有缺钙症状伴行走困难发生率为1．4％（3／220）；对照组分别为53．1％（102／192）、20．8％（40／192）、4．7％（9／192），两组比较差异均有统计学意义（χ2值分别为44．62、17．40、3．92，P均＜0．05）；补钙组妊娠期高血压疾病发病率低于对照组[4．55％（10／220）与10．9％（21／192）]，差异有统计学意义（χ2＝5．95，P＜0．05）；两组的分娩方式及产程时间比较差异均无统计学意义（ P均＞0．05）。结论妊娠期系统补钙有利于减少低钙症状，降低妊娠期高血压疾病的发病率，且对妊娠结局无影响。Objective To investigate the effect of calcium supplementation during pregnancy on clinical symptoms,the incidence of gestational hypertension and childbirth labor. Methods A set of pregnant women in the same season and the same gestation age（20 weeks later） with the age of 20-35 years old in Maternal and Child Health Care Hospital of Haidian District of Beijing were selected as research subjects,according to its cal-cium circumstances,divided into calcium group with 220 cases,who took 600 mg calcium every day from 20 week of pregnancy to delivery,and control group with 192 cases who didn＆#39;t supplement calcium or supplement calcium but not regular or amount was not up to standard. The serum calcium of 20 weeks and 36 weeks of pregnancy were measured,the incidence of calcium deficiency symptoms during pregnancy, the incidence of hypertension during pregnancy,the termination of pregnancy and the labor time were observed. Results The incidence of lumbar and sacral pain,gastrocnemius muscle spasm and calcium deficiency symptoms accompanied with diffi-culty walking of calcium group were 21. 4%（ 47/220） ,6. 8%（ 15/220） and 1. 4%（ 3/220） ,significantly lower than the control group（53. 1%（102/192）,20. 8%（40/192） and 4. 7%（9/192））,the differences were signifi-cant（χ2=44. 62,17. 40,3. 92;P〈0. 05） . The incidence of gestational hypertension of calcium group was lower than the control group（ 4. 55%（ 10/220） vs. 10. 9%（ 21/192）;χ2=5. 95,P〈0. 05） . The calcium group and the control group had no significant difference in the mode of delivery and labor time（ P〉0. 05） . Conclusion Cal-cium supplementation during pregnancy helps reduce system hypocalcemia symptoms, reduce the incidence of gestational hypertension,but have no effect on pregnancy outcome.

关 键 词：妊娠期 补钙 妊娠结局 妊娠期高血压疾病 

分 类 号：R977.9[医药卫生—药品]