肝移植术后早期门静脉血栓形成的诊治及研究进展  

Diagnosis and treatment of early portal vein thrombosis after liver transplantation and research progress

作　　者：唐涛[1] 杜成友[1] 杨志明[1] 

机构地区：[1]成都医学院第一附属医院肝胆外科,610500

出　　处：《中国综合临床》2016年第9期850-853,共4页Clinical Medicine of China

基　　金：国家临床重点专科建设项目（[2012]649）

摘　　要：早期门静脉血栓形成是肝移植术后少见但严重的并发症，也是导致移植物丢失及受体死亡的主要原因之一。我们通过收集国内外相关资料，对肝移植术后早期门静脉血栓的病因、临床表现、影像学诊断和治疗方法进行归纳和讨论。肝移植术后早期门静脉血栓形成由多个危险因素协同作用导致，其发病率为1％-2％。临床表现隐匿，缺乏特异性。腹部超声与CT血管造影（ CTA）相结合的影像学手段有助于早期临床发现，必要时可磁共振血管造影检查（ MRA）辅助，如各项检查阴性，可行门脉造影检查明确诊断。血管内介入治疗以创伤小、并发症少、成功率高为优势逐渐成为一线治疗方案。而外科手术治疗不仅是传统有效的治疗手段，也是介入治疗失败后有效的补救措施。Early portal vein thrombosis is a rare but serious complication after liver transplantation,also is one of the main causes which lead to graft loss and receptor death. We collected domestic and foreign relevant data,and summarized and discussed the causes, clinical manifestation, imaging diagnosis of early portal vein thrombosis after liver transplantation. Early portal vein thrombosis after liver transplantation caused by multiple risk factors synergy. It was reported incidence of 1% to 2%. Clinical manifestations were concealment and lacked of specificity. Abdominal ultrasound and computed tomography angiography （ CTA） imaging methods of combi-ning could help early clinical findings,When necessary magnetic resonance angiography（ MRA） . If each check negative,portal vein angiography could make a definitive diagnosis. Intravascular interventional therapy with small trauma, less complications and high success rate for advantages gradually became first-line treat-ments. Surgical treatment is not only as traditional effective treatments,but also an effective remedial measures after interventional treatment failure.

关 键 词：肝移植 门静脉血栓 介入治疗 

分 类 号：R657.3[医药卫生—外科学]