2010-2014年乌鲁木齐市某区吸毒人群HIV、HCV、梅毒及其合并感染与危险因素分析  

HIV,HCV,syphilis and their co-infection and risk factors analysis among drug users in Urumqi from 2010 to 2014

作　　者：叶.叶克吉尔格力 张昭[2] 赵小龙 田恬[1] 蔡爱杰[1] 戴江红[1] Ye Yekejiergeli ZHANG Zhao ZHAO Xiaolong TIAN Tian CAI Aijie DAI Jianghong(Department of Epidemilogy and Biostatistics, College of Public Health ,Xinjiang Medical University, Urumqi 830011, China Center for Disease Contral and Prevention （CDC） of Mianyang City Sichuan Province, Mianyang 621000, China Department of STD and AIDS, CDC of Urumqi Saybagh District, Urumqi 830000, China)

机构地区：[1]新疆医科大学公共卫生学院流行病学与卫生统计教研室,乌鲁木齐830011 [2]四川省绵阳市疾病预防控制中心,四川绵阳市621000 [3]乌鲁木齐市沙依巴克区疾病预防控制中心性病艾滋病科,乌鲁木齐830000

出　　处：《新疆医科大学学报》2016年第11期1447-1451,共5页Journal of Xinjiang Medical University

基　　金：国家十一五科技重大专项课题(2008ZX10001-016)

摘　　要：目的了解乌鲁木齐市吸毒人群艾滋病病毒（HIV）、丙型肝炎病毒（HCV）和梅毒螺旋体（TP）及其合并感染状况与其高危行为,为制定有效可行的防控策略提供依据。方法按照《全国艾滋病哨点监测实施方案》,2010-2014年对乌鲁木齐市某区吸毒人群进行监测,收集其人口学特征、艾滋病防治知识知晓情况、感染情况（包括HIV、HCV、梅毒）及其高危因素。结果共监测吸毒者1 725例,男女比为34∶1;以汉族（45.5%）与维吾尔族（39.0%）居多;其艾滋病相关知识知晓率保持较高水平（98.8%）。HIV、HCV、梅毒平均检出率分别为13.0%、43.2%和2.5%;2010-2014年单独HCV感染、HCV及其合并感染率明显不同（χ2=153.2,P〈0.001;χ2=203.4,P〈0.001）,HCV及其合并感染率最高为2012年的67.5%,最低为2014年的24.5%;2010-2014年注射兼并共用针具比例仍较高,达31.4%;安全套利用率不高,一般在50%以下。注射吸毒兼共用针具者更易发生HCV及其合并感染。结论乌鲁木齐市吸毒人群HCV及其合并感染最为严重;HIV及其合并感染仍较严重,与其高知晓率严重偏离;而5年间梅毒及其合并感染状况保持恒定。Objective To understand the infection status of Human Immunodeficiency Virus（ HIV）,Hepatitis C Virus（ HCV）,Treponema Pallidum（ TP） among drug addicts and their risk behaviors in Urumqi,and to provide scientific evidence for making intervention strategies. Methods According to the ＂National HIV Sentinel Surveillance Program＂,drug abusers were in Urumqi were monitored in 2010- 2014,and their demographic characteristics,knowledge of HIV / AIDS prevention and treatment,infection（ including HIV,HCV and syphilis） factors were collected and analyzed. Results A total of 1 725 cases of drug addicts were monitored. The ratio of male to female is 34∶ 1. The Han nationality（ 45. 5%） and the Uighurs（ 39. 0%） were the majority nationalities. The aware of knowledge about HIV / AIDS maintained high levels（ 98. 8%）. HIV,HCV,TP average detection rates were 13.0%,43. 2% and 2. 5%. HCV infection and HCV co-infection rates were significantly different during the five years（ χ2= 153. 2,P〈 0. 001; χ2= 203. 4,P〈 0. 001）. The highest HCV and its co-infection rates infection rate was 67. 5% in 2012 and the minimum rate was 24. 5% in 2014. From 2010 to 2014,the proportion of syringe needle sharing was still high,reaching 31. 4%; condom utilization rate is not high,generally below 50%. Injection of drugs and sharing needles are more prone to cause HCV and its co-infection. Conclusion HCV and its co-infection in Urumqi was the most serious problem among the drug users; HIV and co-infection was still serious,with a high degree deviation from its high awareness; and syphilis infection status in 5 years remained constant.

关 键 词：吸毒 HIV HCV 合并感染 

分 类 号：R18[医药卫生—流行病学]