颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的临床分析  

Clinical Analysis of Reperfusion Injury after Stent Implantation in Carotid Artery Stenosis

作　　者：曾凡猛[1] 方凯[1] ZENG Fan-meng FANG Kai(The Second People＇s Hospital of Zhaoqing, Zhaoqing 526060, Guangdong Province, Chin)

机构地区：[1]广东省肇庆市第二人民医院,广东肇庆526060

出　　处：《罕少疾病杂志》2016年第5期6-7,10,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的影响因素。方法选取我院从2014年1月到2016年3月入院治疗的35例颈内动脉狭窄支架置入血管成形术患者做为研究对象。按照患者颈内动脉狭窄程度分为重度狭窄组15例与中度狭窄组20例。两组患者均采用颈内动脉狭窄支架置入血管成形术治疗,统计两组患者术后再灌注损伤几率及影响因素分析。结果重度狭窄组患者的再灌注损伤率显著高于对照组患者,差异具统计学意义(P<0.05)。颈内动脉狭窄支架置入血管成形术后再灌注损伤发生率的主要影响因素为患者的年龄、合并疾病及狭窄程度。结论通过对颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的发生几率及其影响因素统计分析,患者年龄、合并疾病及狭窄程度等因素对于术后再灌注损伤几率影响较大。Objective To investigate the internal carotid artery stenosis stenting factors postoperative reperfusion injury in shape, Methods In our hospital from January 2014 to March 2016 35 hospitalized patients with carotid artery stenosis stenting in patients undergoing shaping as a research object. In accordance with internal carotid artery stenosis as severe stenosis group and 15 cases of 20 patients with moderate stenosis. Two groups of patients were treated with internal carotid artery stenosis stent angioplasty, the two groups after statistical probability of reperfusion injury and influencing factors. Resu.lts The rate of reperfusion injury in patients with severe stenosis was significantly higher in patients, the difference was statistically significant （P〈0.05）. Internal carotid artery stenosis stenting angioplasty main factors of postoperative reperfusion injury incidence for age, comorbidities and stenosis patients. Conclusion Based on the internal carotid artery stenosis stent angioplasty reperfusion injury risk of the occurrence of postoperative factors and statistical analysis, patient age, comorbidities and other factors stenosis greater chance of postoperative reperfusion injury affected.

关 键 词：颈内动脉狭窄 支架置入血管成形术 再灌注损伤 影响因素 

分 类 号：R543.4[医药卫生—心血管疾病]