某儿童医院感染病房病原菌分布及耐药性分析  

The distribution and resistance of bacteria isolated from infection department of children′s hospital

作　　者：雷旻[1] 周高枫[1] 王红梅[1] 王和平[1] 张交生[1] 齐利峰[1] 彭宝玲[1] 邓继岿[1] 

机构地区：[1]广东省深圳市儿童医院感染科

出　　处：《国际检验医学杂志》2016年第19期2702-2704,2707,共4页International Journal of Laboratory Medicine

摘　　要：目的调查感染科病房患儿标本细菌培养的情况,了解其病原菌种类及其对常用抗菌药物的耐药性。方法 2014年1月1日至12月31日该院感染科收治的3 745例患儿,送检各类细菌培养标本4 998份,进行病原学统计。结果 3 745例患儿,以手足口病为主,占37.30%,其次是支气管肺炎、轮状病毒肠炎和细菌性肠道感染;细菌培养共检出细菌784株,主要为副流感嗜血杆菌(16.20%)、肺炎链球菌(14.92%)、卡他莫拉菌(12.88%)、金黄色葡萄球菌(10.59%)和沙门菌属(10.08%);金黄色葡萄球菌中耐甲氧西林的阳性率为27.50%,大肠细菌为46.43%,肺炎克雷伯菌为81.40%;可检出2种以上细菌的类型主要是痰培养标本。结论该院感染病房的病原菌分布以嗜血杆菌属、肺炎链球菌、卡他莫拉菌为主,且存在一定的耐药性。合理选用抗菌药物以控制耐药细菌传播。Objective To investigate the distribution of pathogens isolated from clinical samples and the resistance to the common antimicrobial agents.Methods Of the 3 745 children,Hand-foot-mouth disease was the most prevalent disease with 1 397（37.30%）cases,followed by the bronchopneumonia,rotavirus enteritis and bacterial intestinal infection;784strains were isolated from the samples mainly including Haemophilus parainfluenzae（16.20%）,Streptococcus pneumoniae（14.92%）,Moraxella catarrhalis（12.88%）,Staphylococcus aureus（10.59%）and Salmonella enterica（10.8%）;The positive rate of Methicillin-resistance Staphylococcus aureus（MRSA）was 27.50% and the ESBLs producing Escherichia coli and Klebsiella pneumoniae were 46.43%and 81.40%,and two or more pathogens could be isolated from sputum.Conclusion Haemophilu,Streptococcus pneumonia and Moraxella catarrhalis are the main bacterial pathogens in the department of infectious.There is a certain resistance to the common antimicrobial agents.It is important for us to focus on the pathogens and we should pay more attention to the control the resistance of the bacteria.

关 键 词：感染病房 儿童 病原学 

分 类 号：R446.5[医药卫生—诊断学] R197.5[医药卫生—临床医学]