RAFT聚合法制备丙烯酰胺纳米凝胶的工艺优化  

Process Optimization of Acrylamide Nanogels Prepared by RAFT Polymerization

作　　者：龚霞[1] 胡莹莹[1] 尤祥宇[1] 谢卫红[1] 

机构地区：[1]湖北工业大学,湖北武汉430068

出　　处：《化学与生物工程》2016年第10期35-38,44,共5页Chemistry & Bioengineering

基　　金：中科院病毒所国家重点实验室开放研究基金资助项目(20875024)

摘　　要：对聚合物的粒径和分散性的精密控制是当前聚合物研究的重要课题。采用可逆加成-断裂链转移(RAFT)聚合法制备了丙烯酰胺纳米凝胶,考察了聚合时间、单体(AAm)+交联剂(EGDMA)用量、链转移剂(BDC)+引发剂(AIBN)用量、BDC用量、n(AAm)∶n(EGDMA)比值、聚合温度等对制备工艺的影响。结果表明,当延长聚合时间、增加AAm+EGDMA用量、升高聚合温度、减少BDC+AIBN用量、减少BDC用量、减小n(AAm)∶n(EGDMA)比值时,纳米凝胶的粒径和分散性增大;且粒径基本上与分散性呈正相关关系。通过控制反应条件,可以得到单分散、粒径在几十到几百纳米的丙烯酰胺纳米凝胶。Precision control of the particle size and dispersity of polymers is an important topic of current polymer research.Acrylamide nanogels were prepared by reversible addition-fragmentation chain transfer（RAFT）polymerization.The effects of polymerization time,dosage of monomer（AAm）and cross-linker（EGDMA）,dosage of chain transfer agent（BDC）and initiator（AIBN）,dosage of BDC,n（AAm）∶n（EGDMA）ratio,and polymerization temperature on preparation process were investigated.Results indicated that,when increasing the polymerization time,the dosage of AAm＋EGDMA,polymerization temperature,and reducing the dosage of BDC＋AIBN,the dosage of BDC,n（AAm）∶n（EGDMA）ratio,the particle size and dispersity of nanogels increased.There was a positive correlation between the particle size and the dispersity.By controlling the reaction conditions,the monodispersed acrylamide nanogel was prepared,and its particle size was in the range of tens to hundreds of nanometers.

关 键 词：可逆加成-断裂链转移(RAFT)聚合 丙烯酰胺 纳米凝胶 优化 

分 类 号：TQ317[化学工程—高聚物工业]