感冒退热颗粒提取液热物性参数的测定及模型的建立  

Determination of thermal physical parameters and model establishment for Ganmao Tuire Granule extract

作　　者：孟庆卿 王宝华[1] 杨贝贝[1] 季文琴[1] 李萍[1] 王芳[1] 丁磊[1] 

机构地区：[1]北京中医药大学中药学院,北京100102

出　　处：《北京中医药大学学报》2016年第9期759-763,共5页Journal of Beijing University of Traditional Chinese Medicine

摘　　要：目的测定感冒退热颗粒提取液在不同温度、不同浓度下的导热系数以及不同浓度下的比热容,建立提取液的导热系数-温度、导热系数-浓度、导热系数-温度-浓度及比热容-浓度的数学模型。方法采用瞬时双热线法导热系数仪、电热法比热容测定仪测定导热系数λ和比热容cp。运用Excel、1stOpt、MATLAB等数据处理软件对实验数据进行分析。结果初步确定中药提取液导热系数与温度、浓度的关系均为线性负相关(λ=a-b T,λ=a-b C),且温度、浓度对导热系数的影响存在一定作用,λ=a-b C-c T-d CT可以作为温度、浓度对导热系数的综合作用模型。初步确定中药提取液的比热容与浓度呈线性负相关,可表示为cp=a-b C。结论本文以感冒退热颗粒提取液为考察对象,表明中药提取液在不同温度、浓度条件下的导热系数和比热容差异较大。感冒退热颗粒提取液热特性的考察及相关模型的建立,为中药及天然药物提取液在热物性参数方面研究提供了数据支持及理论指导,对中成药生产设备的选型和设计、生产过程控制等具有指导意义,对中药生产关键技术的研究提供数据支持。Objective To determine the thermal conductivity coefficient（ λ） under different temperatures（ T） and different concentrations（ C） and specific heat capacity（ cp）,so as to establish the mathematical models of λ-T,λ-C,λ-T-C and cp-C of Ganmao Tuire Granules extract. Methods λ and cpwere determined by using instantaneous double line method and equivalent specific heat capacity meter respectively. Then the experimental data were analyzed using software Excel,1stOpt and MATLAB. Results There was a negative linear correlation between λ and T,λ and C（ λ = a- b T,λ = a- b C）,furthermore,T and C had certain interactions on influence of λ. λ = a- b C- c T- d CT can be used as a combination model of temperature and concentration on the coefficient of thermal conductivity. In addition,cp had linear negative correlation with C（ cp= a- b C）. Conclusion Taking Ganmao Tuire granules extract as subject,this study proved the great difference of λ and cpof Chinese medicine extract under different temperature and concentration. This study provided data support and theoretical guidance of thermal-physical parameters,of selection and design the medicine production equipment,of production process control,and of the key technology of production.

关 键 词：感冒退热颗粒 提取液 导热系数 比热容 数字模型 

分 类 号：R284.2[医药卫生—中药学]