80kV条件下碘克沙醇（270mgI/mL）在CTPA检查中的研究  

Study of pulmonary angiography using iodixanol（270 mg I/mL）with 80 kV technique

作　　者：潘自兵[1] 马小彦[1] 刘小康[1] 赵凯[1] 田博[1] 平学军[1] PAN Zibing MA Xiaoyan LIU Xiaokang ZHAO Kai TIAN Bo PING Xuejun(Department of Radiology ,Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University ,Yinchuan 750002,Chin)

机构地区：[1]宁夏医科大学总医院心脑血管病医院放射科,宁夏银川750002

出　　处：《实用放射学杂志》2016年第10期1598-1601,共4页Journal of Practical Radiology

基　　金：宁夏医科大学科学研究基金（XZ2015009）。

摘　　要：目的：探讨80 kV 条件下碘克沙醇（270 mg I/mL）应用于 CT 肺动脉血管成像（CTPA）检查的可行性。方法将90例拟行 CTPA 检查的患者随机分为 A 组和 B 组。A 组45例：应用270 mg I/mL 碘对比剂同时使用自适应统计迭代重建（ASIR）,管电压为80 kV,自动 mA；B 组45例：应用370 mg I/mL 碘对比剂同时使用滤波反投影（FBP）重建,管电压为120 kV,自动 mA。2组使用对比剂的总量均为40 mL。记录2组的容积 CT 剂量指数（CTDI）、剂量长度乘积（DLP）。对2组图像质量进行双盲法评分；采用两独立样本 t 检验比较2组患者的有效辐射剂量、平均 CT 值、图像噪声、图像信噪比（SNR）、对比噪声比（CNR）、图像质量评分等,并对2组患者的阳性率以及碘摄入量进行比较。结果CTPA 共检查出肺动脉栓塞（PE）53例（A 组24例,B 组29例）,A组显示 PE 的阳性率（53.33%）与 B 组（64.44%）差异均无统计学意义。2组均可以显示4~6级肺动脉分支,图像质量均符合诊断要求,主观评分的差异无统计学意义（P 〉0.05）。2组患者的性别、年龄和体质量指数（BMI）的差异均无统计学意义。A 组的肺动脉平均 CT 值和噪声分别高于 B 组,差异有统计学意义（P 〈0.01）。A 组的 SNR 和 CNR 低于 B 组,差异有统计学意义（P 〈0.01）。结论在80 kV 条件下应用碘克沙醇（270 mg I/mL）行 CTPA 检查,获得的图像可满足临床需求,降低了辐射剂量并减少了对比剂的摄入量。Objective To evaluate the feasibility of using a 80 kV tube voltage and iodixanol（270 mg I/mL）as contrast medium in CT pulmonary angiography （CTPA）.Methods 90 patients performed CTPA examination were divided into two groups：Group A （n=45）, auto mA,80 kV tube voltage and 270 mg I/mL contrast medium and sinogram-affirmed iterative reconstruction （SAFIRE）;Group B （n=45）,120 kV tube voltage,370 mg I/mL contrast medium and filtered back projection reconstruction（FBP）.Both with 40 mL contrast medium.The CT dose index （CTDI）and dose length product （DLP）were recorded.The image quality were assessed by two experienced radiologists with adouble blinded fashion in a five score scale.Image quality,image noise,signal-to-noise ratio （SNR）,contrast-to-noise ratio （CNR）,radiation dose and iodine intake were compared between two groups using two sample t test. Results PE was found in 53 patients （24 in group A,29 in group B）.There was no significant difference of the positive rate of PE between two groups.All 4-6 pulmonary artery branches were clearly displayed in all cases.There was no statistical difference between two groups in the image quality scores（P 〉0.05）.No significant statistical difference was found in sex,ageand body mass index （BMI）of these groups.The average CT value and noise in group A was higher than those in group B,which was statistically significant（P〈0.01）.But the SNR and CNR in group A were lower than those in group B.There was statistically significant difference between two groups（P 〈0.01）. Conclusion Using 80 kV tube voltage technique and iodixanol（270 mg I/mL）for CTPA,the image quality could meet the requirment for clinical diagnosis,the radiation dose and the volume of contrast medium could be lowered.

关 键 词：肺栓塞 对比剂 辐射剂量 计算机体层成像 血管造影术 

分 类 号：R563.5[医药卫生—呼吸系统] R814.42[医药卫生—内科学]