老年代谢综合征与动脉硬化进展的相关性研究:北上海社区老年人心血管病研究  

Correlation between Metabolic Syndrome and Arterial Stiffness in Elderly People:A Population-based Study in Communities of Northern Shanghai

作　　者：秦艳莉[1] 王凯[1] 吕煜焱 熊婧[1] 白彬[1] 于世凯[1] 周益武 迟琛 张毅[1] 徐亚伟[1] 

机构地区：[1]同济大学附属第十人民医院心内科,上海200072

出　　处：《中国循证医学杂志》2016年第10期1127-1130,共4页Chinese Journal of Evidence-based Medicine

基　　金：上海市卫计委重要疾病联合攻关重大项目(编号:2013 ZYJB 0902)

摘　　要：目的探讨老年人中代谢综合征(MS)与动脉硬化进展之间的关系。方法纳入北上海10个社区的1 599名老年居民(年龄>65岁)为研究对象。采用Sphygmo Cor动脉硬化检测仪检测患者颈-股脉搏波传导速度(cf-PWV)。MS各诊断要素均采用常规检查方法检测。采用SPSS 20.0软件进行统计分析。结果 cf-PWV与MS诊断要素均呈显著的相关性(P<0.001)。而且,随着MS诊断要素个数的累积,cf-PWV呈逐渐上升的趋势。这种趋势在全部人群、男性及女性中均达到了统计学显著性标准(P<0.001)。结论动脉硬化与MS各个诊断要素均显著相关,且随着MS诊断要素的累积而逐渐增加。Objective To investigate the association between metabolic syndrome and arterial stiffness in elderly people. Methods 1 599 participants aged over 65 years old were recruited from 10 communities located in the northern Shanghai. Carotid-femoral pulse wave velocity（cf-PWV） of each participant was measured by Sphygmo Cor device. Measurements for the diagnosis of metabolic syndrome were all investigated for each participant. SPSS 20. 0 was used for data management and statistical analysis. Results Cf-PWV was significantly associated with metabolic syndrome and its diagnostic measurements（P〈0. 001）. Moreover, with the accumulating diagnostic measurements, cf-PWV increased gradually and significantly. The increasing trend remained significant in all participants, in men and in women（P〈0. 001）. Conclusion Arterial stiffness is significantly associated with metabolic syndrome and the accumulation of its diagnostic measurements.

关 键 词：老年人 动脉硬化 代谢综合征 脉搏波传导速度 人群研究 

分 类 号：R589[医药卫生—内分泌]