发作性睡病的危险因素研究进展  

Research progress in risk factors for narcolepsy

作　　者：郎奕[1] 王少杰[1] 俞杰[1] 梁楚西 杨嘉颐[1] 张一帆[1] 吴玉梅 

机构地区：[1]北京大学人民医院,北京100044 [2]装备发展部门诊部,北京100011

出　　处：《现代预防医学》2016年第20期3818-3821,共4页Modern Preventive Medicine

基　　金：国家自然基金课题-发作性睡病与中医体质关系的初步研究(NO.81273712)

摘　　要：发作性睡病是一种以突发不可抗拒的睡眠、猝倒发作,不自主运动,睡瘫笑瘫及入睡幻觉为主要症状的慢性睡眠障碍性疾病,严重影响患者学习、工作和生活质量。目前,该病的发病诱因及机制尚不明确,且缺乏长期有效的治疗手段。本文遵循未病先防,已病防变的中医理念,对发作性睡病危险因素的研究概况进行系统综述,旨为临床预防及中西医治疗该病提供帮助。Narcolepsy is a chronic sleep disorder with the main symptoms being sudden and irresistible sleep, cataplexy attack, involuntary movement, sleep paralysis, laugh paralysis and hypnogogic hallucination. The disorder significantly influences learning, working and life quality of the patients. At present, the etiological factors and mechanism of such disorder is yet unclear, and long-term, effective therapeutic approaches are lacking. By following the concept in traditional Chinese medicine of prevention before illness and prevention of pathological changes during illness, this article systematically summarizes the research progress in risk factors for narcolepsy, aiming to offer guidance for clinical prevention and combined treatment of narcolepsy.

关 键 词：发作性睡病 危险因素 遗传因素 环境因素 

分 类 号：R338.63[医药卫生—人体生理学]