骨松宝胶囊治疗胸腰段椎体压缩性骨折的临床效果  

Effect of gusongbao capsule on thoracolumbar vertebral compression fractures

作　　者：王健[1] 

机构地区：[1]新疆维吾尔自治区克拉玛依市中心医院骨科,834000

出　　处：《中国实用医刊》2016年第20期120-121,共2页Chinese Journal of Practical Medicine

摘　　要：目的探讨骨松宝胶囊治疗胸腰段椎体压缩性骨折的临床效果。方法收集骨质疏松性胸腰段椎体压缩骨折患者32例，口服骨松宝胶囊、钙尔奇D，比较治疗前后腰椎骨密度。结果失访4例。治疗6个月随访时，患者腰椎骨密度变化较为明显，治疗后骨密度较治疗前升高，且差异有统计学意义（t=2．032，P〈0．05）。治疗9个月随访时，患者腰椎骨密度变化更为明显，较治疗6个月时明显升高，且差异有统计学意义（t=2．035，P〈0．05）。结论在骨松宝胶囊治疗骨质疏松性胸腰段椎体压缩骨折时，长期服药安全有效，建议服药时间应至少持续6个月，为巩固和提高疗效服药时间可超过9个月。Objective To investigate the effect of gusongbao capsule on thoracolumbar vertebral compression fractures. Methods Thirty - two patients with thoracolumbar vertebral compression fractures were selected, they were given gusongbao capsule and caltrate D, lumbar spine bone mineral density before and after the therapy was compared. Results Four cases were lost to follow-up. When the medication continued followed-up for six month, the significant changes were observed in the lumbar spine bone mineral density, the bone mineral density （BMD） in the patients taking gusongbao capsules was significantly increased compared with before treatment, and the difference was significant（ t = 2. 032, P 〈 0. 05）. While after nine months followed-up, BMD significantly increased compared with that of six months after treatment, and the difference was significant （ t = 2. 035, P 〈 0. 05 ）. Conclusions The long-term medication of gusongbao capsule in treating osteoporotic thoracolumbar vertebral compression fractures is safe and effective, so we recommend the period should last for six months at least, or even for nine months or more in order to consolidate and improve the efficacy.

关 键 词：胸腰椎 压缩性骨折 骨松宝胶囊 

分 类 号：R683[医药卫生—骨科学]