年龄因素对女性尿失禁患者尿动力学参数的影响  

Effect of age on urodynamic parameters of women with urinary incontinence

作　　者：张维宇[1] 张晓鹏[1] 陈京文[1] 孙屹然[1] 王佳[1] 胡浩[1] 许克新[1] 

机构地区：[1]北京大学人民医院泌尿外科,北京100044

出　　处：《北京大学学报（医学版）》2016年第5期825-829,共5页Journal of Peking University:Health Sciences

摘　　要：目的：分析女性尿失禁患者术前尿动力学参数随年龄增长的变化趋势。方法：回顾性分析2008年5月至2015年10月间北京大学人民医院泌尿外科收治的214例尿失禁患者的临床资料,患者年龄30～82岁,平均（56.97±10.68）岁,病史1个月至50年,平均（8.44±8.85）年。尿动力学检查均在北京大学人民医院泌尿外科于术前常规进行,分为非侵入性检查和侵入性检查两部分,包括最大尿流率、平均尿流率、达到最大尿流率的时间、排尿时间、最大尿流率时逼尿肌压、最大逼尿肌压、排尿量、残余尿量、膀胱总容量、初始尿意、强烈尿意、急迫尿意和漏尿点压力等参数。按年龄将患者分为4组进行比较,使用Kolmogorov-Smirnov检验和单因素方差分析对数据进行分析。结果：共纳入214例患者资料,最大尿流率、平均尿流率、排尿量、膀胱总容量随年龄增长而显著下降,差异有统计学意义,残余尿量、排尿时间随年龄增长而上升,最大逼尿肌压随年龄增长而逐渐下降。结论：女性尿失禁患者随年龄增加,尿动力学参数发生变化,主要表现为最大尿流率、平均尿流率、排尿量、膀胱总容量显著下降,残余尿量、排尿时间随年龄增加上升,最大逼尿肌压随年龄增加下降。Objective： To investigate age related changes in urodynamic parameters of women with urinary incontinence. Methods： From May 2008 to October 2015,a total of 214 patients diagnosed with urinary incontinence in Peking University People＇s Hospital was involved in this study. Average age was（ 56. 97 ± 10. 68） years,ranging from 30 to 82 years,and average history was（ 8. 44 ± 8. 85） years,ranging from one month to 50 years. Urodynamic examinations of each patient were taken before operation routinely in Department of Urology,Peking University People ＇s Hospital. The urodynamic study was composed of non-invasive and invasive procedures. Analysis included maximal flow rate（ Qmax）,average flow rate,time to Qmax,voiding time,detrusor pressure at Qmax,maximal detrusor pressure,voided volume,post-void residual urine volume（ PVR）,the total capacity of bladder,first-,strong-,and urgedesire to void,cough leak point pressure（ CLPP）,and Valsalva leak point pressure（ VLPP）. Patients were divided into four groups according to age,Kolmogorov-Smirnov test and one-way ANOVA were used for data analysis. Results： A total of 214 patients were enrolled in this study. The data of Qmax,average flow rate,voided volume,and total capacity of bladder decreased with statistical significance. The value of residual urine volume and voiding time increased without statistical significance,while the value of maximal detrusor pressure decreased. Conclusion： Urodynamic examination data of females with urinary incontinence changes along with the elapse of age,which was mainly observed as age ascends,and the changes in urodynamic parameters of women with urinary incontinence suggest that the value of Qmax,average flow rate,voided volume,and total capacity of bladder decreased significantly,while the value of PVR and the voiding time increased and the value of maximal detrusor pressure decreased.

关 键 词：年龄因素 女性 尿失禁 尿动力学 

分 类 号：R694[医药卫生—泌尿科学]