Photochemistry and pharmacology of 9,19-cyclolanostane glycosides isolated from genus Cimicifuga  

作　　者：SU Yang CHI Wen-Cheng WU Lun WANG Qiu-Hong KUANG Hai-Xue 

机构地区：[1]Department of Microbiology,Immunology&Molecular Genetics,University of California Los Angeles,Los Angeles,CA 90025,USA [2]Key Laboratory of Chinese Materia Medica,Department of Pharmacology,Heilongjiang University of Chinese Medicine,Harbin 150040,China [3]The University of Sydney,NSW 2006,Australia

出　　处：《Chinese Journal of Natural Medicines》2016年第10期721-731,共11页中国天然药物（英文版）

基　　金：supported by National Natural Science Foundation of China(Nos.81603416,81274034);the Fund of Education Department of Heilongjiang Province,China(Nos.12541755,12541752);the Natural Science Foundation of Heilongjiang Province(No.H201472)

摘　　要：The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga rather than in other members of the Ranunculaceae family. So far, more than 140 cycloartane triterpene glycosides have been isolated from Cimicifuga spp.. The aim of this review was to summarize all 9, 19-cyclolanostane triterpenoid glycosides based on the available relevant scientific literatures from 2000 to 2014. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga rather than in other members of the Ranunculaceae family. So far, more than 140 cycloartane triterpene glycosides have been isolated from Cimicifuga spp.. The aim of this review was to summarize all 9, 19-cyclolanostane triterpenoid glycosides based on the available relevant scientific literatures from 2000 to 2014. Biological studies of cycloartane triterpene glycosides from Cimicifi^ga spp. are also discussed.

关 键 词：Cimicifuga spp 9 19-Cyclolanostane glycosides Chemical structure Biological effects 

分 类 号：R284[医药卫生—中药学] R965[医药卫生—中医学]