无症状胆囊结石预后影响因素分析  

Analysis on influence factors of asymptomatic cholecystolithiasis prognosis

作　　者：蔡飞[1] 金亮[1] 李琪[1] 陈骞 张怀 张示杰[1] 

机构地区：[1]石河子大学第一附属医院肝胆外科,新疆石河子832000

出　　处：《局解手术学杂志》2016年第11期837-840,共4页Journal of Regional Anatomy and Operative Surgery

基　　金：新疆生产建设兵团科技计划(2013AB026);国家科技支撑计划(2013BAI05B05)

摘　　要：目的研究无症状胆囊结石患者预后情况并分析预后的影响因素。方法收集石河子大学医学院第一附属医院肝胆外科门诊自2013年12月至2016年3月诊断为无症状胆囊结石的227例患者的临床资料,对无症状胆囊结石患者进行随访问卷调查,最终纳入分析192例,其中57例患者出现临床症状为症状组,135例患者未出现临床症状为无症状组。对影响2组患者预后的因素进行单因素和多元Logistic回归分析。结果单因素分析显示2组结石数量、结石大小、糖尿病、高脂饮食、体重指数比较,差异均有统计学意义(P<0.05)。进一步行Logistic回归分析发现多发结石、结石直径大于等于1 cm、糖尿病是无症状胆囊结石预后的主要危险因素。结论多发结石、结石直径大于等于1 cm、糖尿病、高脂饮食、肥胖可能是影响无症状胆囊结石预后的主要因素。Objective To study the prognosis of patients with asymptomatic gallstones and explore prognostic factors. Methods The clinical data of 227 patients with asymptomatic gallstones in the First Affiliated Hospital of Shihezi University from December 2013 to March2016 were collected. All patients were followed with questionnaire,finally 192 cases were had been enrolled,of which 57 cases with clinical symptoms were symptom group and 135 cases with no clinical symptons were asymptomatic group. The prognostic factors were analyzed by univariate and multivariate logistic regression. Results Univariate analysis showed that there were statistically significant difference in the number of stones,stone size,diabetes,high fat diet and body mass index between the two groups（ P〈0. 05）. The Logistic regression analysis showed that multiple stones,stone diameter ≥1 cm,diabetes were the major risk factors for prognosis in asymptomatic gallstones. Conclusion Multiple gallbladder stones,stone diameter ≥1 cm,diabetes,high fat diet and obesity may be the major prognostic factors for patients with asymptomatic gallstones.

关 键 词：无症状胆囊结石 预后 LOGISTIC模型 影响因素 

分 类 号：R657.4[医药卫生—外科学]