寻常性银屑病患者血清中抗两种分枝杆菌LAM抗原抗体的检测  

Detections of Antibodies Against Two Kinds of LAM Antigens of Mycobacteria in Serum from Patients with Psoriasis Vulgaris

作　　者：靳亚莉[1] 张振国[1] 乐宏元[1] 王绘翔[1] 鹿红艳 吕成志[1] 宋顺鹏[1] 

机构地区：[1]大连市皮肤病医院,辽宁大连116000

出　　处：《中国皮肤性病学杂志》2016年第11期1104-1106,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的检测寻常性银屑病患者血清中是否存在抗结核分枝杆菌和抗麻风分枝杆菌LAM抗原的抗体。方法分别用结核分枝杆菌和麻风分枝杆菌胞壁的LAM成分作抗原和间接酶联免疫吸附试验(ELISA)检测寻常性银屑病患者和正常对照者血清中是否有抗上述抗原之抗体的存在,并对结果进行统计学比较分析。结果寻常性银屑病患者血清中存在很高含量的抗两种LAM抗原的抗体,且其水平相当,与正常对照比较差异有统计学意义。结论寻常性银屑病患者血清中存在高水平的抗结核分枝杆菌和麻风杆菌胞壁的LAM成分的抗体。Objective To detect whether there are antibodies against LAM antigens of M.tuberculosis and M.leprae in sera from patients with psoriasis vulgaris.Methods The levels of serum antibodies against two kinds of LAM antigens of Mycobacteria above mentioned in patients with psoriasis vulgaris and normal controls were detected with ELISA and relevant analyses were satistically conducted.Results The high levels of antibodies against the two LAMs in patients with psoriasis vulgaris were present, and both of which are statistically significant difference from normal controls.Conclusion There are high levels of antibodies against the LAM antigens of M.tuberculosis and M.leprae in sera of patients with psoriasis vulgaris.

关 键 词：寻常性银屑病 LAM 酶联免疫吸附试验 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]