单次高危性行为后即感染HIV的男男同性恋者1例随访分析  

The Follow up and Analysis of HIV Infected by A Single High Risk Sexual Behavior in a Case of Man Who have Sex with Man

作　　者：蔡英[1] 赵金仙[1] 付金翠[1] 郭春园[1] 鲁建波[1] 李世福[1] 

机构地区：[1]云南省玉溪市疾病预防控制中心,云南玉溪653100

出　　处：《中国皮肤性病学杂志》2016年第11期1147-1149,1156,共4页The Chinese Journal of Dermatovenereology

摘　　要：目的对仅发生过一次无保护肛交男男同性恋者进行追踪随访和检测以判定其是否感染HIV,并在随访过程中采集血清保存。方法发生高危肛交性行为后对该患者进行4次追踪检测,抽血进行HIV(human immunodeficiency virus,HIV)抗体筛查和确证试验、CD4^+T淋巴细胞检测以及病毒载量检测,梅毒螺旋体抗原血清检测。结果 HIV抗体酶联免疫吸附试验(ELISA)检测值/临界值(S/CO)持续上升,HIV-1抗体蛋白印迹法(WB)出现的条带越来越多直至全带型,病毒载量检测值越来越高至5600cp/mL,最终诊断为HIV感染,CD4^+T淋巴细胞计数随着HIV-1病毒载量的上升应激性升高,梅毒螺旋体抗原血清检测阴性。结论对高危人群HIV抗体不确定者的追踪随访至关重要,规范采集保存此类血清标本具有极高的研究价值。Objective To follow up a case of man who have sex with man after only one time of unprotected anal sex and to determine the HIV infection status, collect and conserve the serum of every follow up.Methods The four times follow up and testing was carried out after one time of unprotected anal sex, blood was drawn for HIV antibody ELISA and confirmatory testing, CD4＋ T cell counts and HIV viral load testing, and for syphilis antibody testing.Results The S/CO of HIV antibody ELISA appeared rising trend, more and more stripe appeared in confirmatory testing through western blot, HIV viral load higher and higher up to 5 600 cp/mL, eventually diagnosed as HIV infected, and the counts of CD4＋ T cell appeared stress rise along with rise of HIV viral load, syphilis antibody testing result was negative.Conclusion The follow up of people with high risk behavior when WB result was uncertain were of great importance, collected and conserved this kind of serum normatively would have high research value.

关 键 词：高危性行为 HIV 男男同性恋 随访 检测 

分 类 号：R512.91[医药卫生—内科学]