腰痛康胶囊的质量标准研究  

Quality standard research of Yaotongkang Capsules

作　　者：徐倩[1] 邱慧[1] 

机构地区：[1]南昌市洪都中医院制剂中心,江西南昌330008

出　　处：《中国当代医药》2016年第29期7-11,共5页China Modern Medicine

基　　金：江西省南昌市重点攻关及产业化科技项目(洪科发计字[2009]171号)

摘　　要：目的 建立腰痛康胶囊的质量标准。方法 采用薄层色谱法（TLC）对处方中续断、独活、狗脊等药材进行薄层鉴别;反相高效液相色谱法（HPLC）测定腰痛康胶囊中淫羊藿苷的含量。结果 TLC中斑点清晰、分离良好;HPLC测定淫羊藿苷进样量在0.21~2.1μg范围内线性关系良好（r=0.9984）,平均加样回收率（n=5）为99.2%,RSD（n=5）为0.25%。结论 本方法操作简便、专属性强、准确度高、精密度和重复性好,可作为该制剂的质量控制标准。Objective To establish the quality standards of Yaotungkang Capsules.Methods Radix dipsaei,angelica wolf- herry,rhizoma etc. medicinal materials in the prescription were identified hy using thin layer chromatography （TLC）; content of epimedium glycoside in Yaotongkang Capsules was detected by reverse phase high performanee liquid chromatography （HPLC） method.Results TLC spots were clear and well separated;HPLC for sample size of epimedium gly- coside in the range of 0.21-2.1 μg was good （r=0.998 4）,average recovering rate was 99.2% （n=5）,RSD was 0.25% （n= 5）.Conclusion The method has the advantages of simple operation,strong specificity,high aceuraey,goud preeision and repeatability,and can be used as the qualily control standard of the preparation.

关 键 词：质量标准 腰痛康胶囊 薄层色谱法 高效液相色谱法 

分 类 号：R927.2[医药卫生—药学]