消痰解郁方对急进西部高原军人睡眠质量的影响  

Effect of Xiao-tan-jie-yu Prescription on sleep quality of soldiers acute exposure to high altitude

作　　者：杨玉兴[1] 李晓云[2] 魏品康[3] 安花花[4] 蔺彩娟[1] 贺雅萍[5] 郭建魁[6] 权元文 

机构地区：[1]兰州军区兰州总医院中医科 [2]兰州军区兰州总医院医务部 [3]第二军医大学长征医院中医科 [4]兰州军区兰州总医院医学心理科 [5]兰州军区兰州总医院放射科 [6]兰州军区兰州总医院科训科 [7]兰州军区68108部队

出　　处：《解放军医学杂志》2016年第10期869-873,共5页Medical Journal of Chinese People's Liberation Army

基　　金：兰州军区医药卫生科研面上项目(CLZ13JB06);总后保健专项课题(13BJZ06)~~

摘　　要：目的观察中药消痰解郁方对急进西部高原军人睡眠质量的影响。方法采用匹兹堡睡眠质量指数量表(PSQI)对550名急进高原军人进行调查,筛选出睡眠障碍军人100例,按照前瞻、完全随机、安慰剂对照方法分为中药治疗组和安慰剂对照组(n=50),共治疗2周,治疗前后测评患者PSQI总分及各因子分,观察临床疗效及不良反应。结果急进高原军人PSQI总分及各因子得分均显著高于正常成人,睡眠紊乱因子分显著高于失眠症患者,总分及其余各因子得分显著低于失眠症患者。消痰解郁方可降低睡眠障碍军人PSQI总分、主观睡眠质量、入睡时间、睡眠时间、睡眠效率等因子分值,差异有统计学意义(P<0.05,P<0.01),总有效率为91.49%,优于安慰剂对照组(P<0.01),且无不良反应。结论急进西部高原军人睡眠质量不佳,消痰解郁方可改善急进西部高原军人睡眠质量,安全有效。Objective To observe the efficacy of Xiao-tan-jie-yu prescription（XTJYF） on sleep quality of the soldiers who acutely exposed to western area of high altitude. Methods In this prospective, completely randomized, parallel, placebocontrolled study, 550 soldiers acutely exposed to western area of high altitude were investigated by the Pittsburgh Sleep Quality Index（PSQI）, 100 soldiers with sleep disorder were selected and divided into two groups（50 each）： treatment group received TCM XTJYF therapy and control group was treated with placebo. After 2 weeks＇ treatment, PSQI total score and respective factor scores before and after treatment were assessed, and clinical therapeutic efficacy and adverse reactions were observed. Results The PSQI total score and respective factor scores of these soldiers were significantly higher than those of normal adults, but significantly lower than those of insomnia patients, while their sleep disorder factor score was significantly higher compared with insomnia patients. XTJYF reduced the total score and some factor scores（subjective sleep quality, time for initiating sleep, total sleep time, and sleep efficiency） for PSQI in the soldiers with sleep disorder, and the overall response rate was 91.49% which is higher than those in the placebo control group（P〈0.05 or 0.01）, without toxic side effects. Conclusions The sleep quality of soldiers who acutely exposed to western area of high altitude in China is not high, and XTJYF may safely and effectively improve the sleep quality.

关 键 词：高海拔 睡眠障碍 消痰解郁方 军事人员 

分 类 号：R338.63[医药卫生—人体生理学] R821.46[医药卫生—基础医学]