弥漫性大B细胞淋巴瘤的磁共振成像诊断与病理结果的对照研究  

MRI findings of diffuse large B cell lymphoma and comparative study on the diagnosis and pathological results

作　　者：黄宇峰[1] 陈建新[1] 张同华[1] 顾佳[1] 

机构地区：[1]江苏省张家港市第一人民医院影像中心,215600

出　　处：《实用医学影像杂志》2016年第5期379-381,共3页Journal of Practical Medical Imaging

摘　　要：目的回顾性分析弥漫性大B细胞淋巴瘤的磁共振成像(MRI)征象及诊断情况,并与临床病理对照。方法回顾性分析24例经临床病理诊断为弥漫性大B细胞淋巴瘤患者的MRI和病理资料。结果本组24例45个病灶,71%为多发,好发于大脑半球、基底节区。MRI诊断准确率为83%;平扫显示T1WI等或稍低信号,T2WI等或稍低信号,均伴随灶周水肿;弥散加权成像(DWI)等或高信号,对应ADC值降低;34个病灶均匀强化,13个"缺口征",9个"尖角征",2例"握拳征",4例累及室管膜,7例累及软脑膜。临床病理证实均为弥漫性大B细胞淋巴瘤。结论弥漫性大B细胞淋巴瘤的MRI征象具有一定特征性,有利于对疾病进行定性诊断。Objective To retrospectively analyze the MRI findings and its diagnosis of diffuse large B cell lym-phoma, and to compared it with clinical pathology. Methods The MRI and pathological data of 24 cases of patients who were diagnosed with diffuse large B cell lymphoma by clinical pathology were retrospectively analyzed. Results There were a total of 45 lesions in the 24 patients of which 71% were multiple, mainly occurring in the cerebral hemisphere and basal ganglia. The diagnostic accuracy of MRI was 83%; Plain scan showed equal or slightly low sig-nal on T1WI and T2WI, with perifocal edema;There was equal or high signal on DWI and the corresponding ADC val-ue decreased. Thirty-four lesions were homogeneously enhanced. There were 13 gap signs, 9 sharp corner signs and 2 fist signs. There were 4 cases with ependymal involvement and 7 cases with pial involvement which were confirmed as diffuse large B cell lymphoma by clinical pathology. Conclusion MRI findings of diffuse large B cell lymphoma are special, which is conducive to the diagnosis of the disease.

关 键 词：淋巴细胞 慢性 B细胞 磁共振成像 病理学 临床 

分 类 号：R445.2[医药卫生—影像医学与核医学] R733.1[医药卫生—诊断学]