养阴化瘀法治疗支气管扩张反复咯血临床研究  

Clinical study of the treatment principle of Yangyin-Huayu for the patients with recurrent ;hemoptysis of bronchiectasis

作　　者：杨辉 侯建兵 

机构地区：[1]陕西省中医医院呼吸科,西安710003 [2]陕西省宝鸡市高新区东社区卫生服务中心中医内科,721000

出　　处：《国际中医中药杂志》2016年第10期898-901,共4页International Journal of Traditional Chinese Medicine

摘　　要：目的：观察养阴化瘀法治疗支气管扩张反复咯血的疗效及对血清CRP影响。方法将符合入选标准的64例患者按随机数字表法分为2组，每组32例。对照组静脉滴注血凝酶、垂体后叶素、乳酸左氧氟沙星氯化钠注射液，治疗组在对照组基础上加用养阴化瘀中药治疗。2组均治疗10 d。采用双光径免疫浊度分析仪检测血清CRP，比较2组治疗前后症状、体征变化，评价临床疗效。结果治疗组总有效率为96.88%（31/32）、对照组为84.38%（27/32），2组比较差异有统计学意义（χ2＝6.372，P＜0.01）。治疗后，治疗组血清CRP[（2.45±1.42）mg/L比（6.19±2.34）mg/L，t＝4.671]水平低于对照组（P＜0.01）；咳嗽[（0.62±0.91）分比（1.34±0.58）分，t＝5.364]、咳痰[（0.14±0.28）分比（0.68±0.72）分，t＝4.035]、咯血[（0.10±0.65）分比（0.62±0.26）分，t＝5.012]、发热[（0.04±0.31）分比（0.76±0.07）分，t＝3.026]、呼吸困难[（0.12±0.41）分比（0.69±0.05）分，t＝4.010]评分低于对照组（P＜0.01）。结论养阴化瘀法配合西医常规疗法可改善支气管扩张反复咯血患者的症状、体征，降低血清CRP水平，止血效果明显。Objective To observe the clinical curative effect and the serum CPR changes by the treatment principle of Yangyin-Huayu for the patients with recurrent hemoptysis of Bronchiectasis. Methods A total of 64 patients were enrolled and divided into 2 groups according to the random number table method, 32 patients in each group. The control group was treated with the injection of blood clotting enzyme, pituitrin, levofloxacin lactate. And the treatment group was treated with the Yangyin-Huayu on the basis of the control group. Two groups were treated for 10 days. The CPR was detected by the double optical path immune turbidity analyzer. And the clinical effects, symptoms and signs scores were compared between before and after treatment and between two groups. Results Compared with the total effective rate of control group 84.38%（27/32）, the treatment group was 96.88% （31/32） and significantly high （χ2=6.372, P〈0.01）. After treatment, the levels of serum CPR （2.45 ± 1.42 mg/L vs. 6.19 ± 2.34 mg/L, t=4.671） in the treatment groupwas significantly lower than that in the control group （P〈0.01）. The scores of cough （0.62 ± 0.91 vs. 1.34 ± 0.58, t=5.364）, sputum （0.14 ± 0.28 vs. 0.68 ± 0.72, t=4.035）, haemoptysis （0.10 ± 0.65 vs. 0.62 ± 0.26, t=5.012）, fever （0.04 ± 0.31 vs. 0.76 ± 0.07, t=3.026）, breathing difficulties （0.12 ± 0.41 vs. 0.69 ± 0.05, t=4.010） in the treatment group were lower than those in the control group （P〈0.01）. Conclusions The treatment principle of Yangyin-Huayu combined with conventional western medicine therapy can improve the patients with recurrent hemoptysisin the fields of symptoms, signs, the serum level of CPR, and total effect rates.

关 键 词：支气管扩张症 咯血 止血药(中药) 化瘀止血 养阴止血 中西医结合疗法 HEMOSTATICS (TCD) 

分 类 号：R259[医药卫生—中西医结合]