呼出气冷凝液在慢性阻塞性肺疾病中的研究进展  

Exhaled breath condensate analysis in chronic obstructive pulmonary disease

作　　者：施晓娟[1] 阎锡新[1] 

机构地区：[1]河北医科大学第二医院呼吸科,石家庄050000

出　　处：《国际呼吸杂志》2016年第19期1493-1497,共5页International Journal of Respiration

摘　　要：呼出气冷凝液（exhaledbreathcondensate,EBC）检测作为一种新的研究肺部疾病的方法,具有无创、简便易行、实时监测、重复性好、患者易耐受等优点。对COPD患者EBC中反映气道炎症、氧化应激状态的生物标记物进行研究有助于COPD的诊断及对药物治疗反应的评估和患者预后的评价。而且EBC中异常炎症介质的研究可能为COPD发病机制开启新思路并发现新的治疗靶点。Exhaled breath condensate （EBC） analysis, as a new way of studying pulmonary diseases, has the advantages of being noninvasive, easily carrying out, real-time monitoring, repeatability and better patients acceptance. Analyzing biomarkers in EBC which reflect airway inflammation and oxidative stress could assist in the diagnosis of chronic obstructive pulmonary disease（COPD）, evaluating response to therapies and defining the prognosis of individual patients. Furthermore, identification of novel inflammatory mediators in EBC may cast new light on the pathogenesis of COPD and identify new therapeutic targets.

关 键 词：呼出气冷凝液 生物学标记物 慢性阻塞性肺疾病 

分 类 号：R563.9[医药卫生—呼吸系统]