慢性阻塞性肺疾病表型的研究进展  

Research advancements on phenotypes of chronic obstructive pulmonary disease

作　　者：李静[1] 刘政[1] 马姣[1] 

机构地区：[1]河北医科大学石油临床医学院呼吸科,廊坊065000

出　　处：《国际呼吸杂志》2016年第19期1507-1511,共5页International Journal of Respiration

摘　　要：COPD是气道和肺组织对香烟烟雾等有害气体或有害颗粒的产生的异常慢性炎症反应，以气流受限为特征并呈进行性发展的一种疾病。COPD患者在病理学、流行病学、生物学、影像学、临床表现、疾病进展、治疗及预后等方面存在明显差异，这种差异使COPD表现出不同的表型，探讨COPD的不同表型间存在的差异及诊治方法与个体化用药对改善疾病预后，提高患者生活质量有重要意义。本文对近年关于COPD表型相关研究进展进行综述。Chronic obstructive pulmonary disease （COPD） is a disease of lung airway to produce cigarette smoke and other harmful gases or harmful particles abnormal chronic inflammatory response, and characterized by airflow limitation and to form a progressive development. COPD patients have significant differences in pathology, epiderniology, biology, imaging, clinical manifestations, disease progression, treatment and prognosis, this differences make COPD exhibit different phenotypes, explore different phenotypes between COPD differences exist in the diagnosis and treatment of personalized medicine, to improve the prognosis and quality of life of patients have an important role. This paper is about the research progress of COPD phenotypes in recent years.

关 键 词：慢性阻塞性肺疾病 表型 综述 

分 类 号：R563.9[医药卫生—呼吸系统]