Effects of Electro-acupuncture at Tongli (HT 5) and Xuanzhong (GB 39) Acupoints from Functional Magnetic Resonance Imaging Evidence  

作　　者：肖娟 张华 常静玲 周莉 谭中建 钟海珍 朱丹 高颖 

机构地区：[1]Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China [2]Key Laboratory of Encephalopathy Treatment of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100700, China [3]Department of Radiology, Dongzhimen Hospital, Beijng University of Chinese Medicine, Beijing 100700, China

出　　处：《Chinese Journal of Integrative Medicine》2016年第11期846-854,共9页中国结合医学杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.81072768);the New Century Excellent Talents in University of the Ministry of Education of China(No.NCET-11-0603);Capital Featured Clinical Research of Beijing Municipal Science and Technology,China(No.Z131107002213094)

摘　　要：Objective: To explore the specificity of Tongli(HT 5) and Xuanzhong(GB 39) paired acupionts in aspects of Deqi sensation and brain activation patterns during electroacupuncture. Methods: In this study, 15 healthy subjects were enrolled. All participants suffered two kinds of functional magnetic resonance imaging(f MRI) examinations randomly: Examination A received electro-acupuncture(EA) at the bilateral Tongli(HT5) and Xuanzhong(GB 39) acupoints(ACU), and examination B received EA at bilateral non-acupoints(NAP). The subjects reported the feeling of Deqi at each examination later respectively. A multi-voxel pattern analysis method and Statistical Program for Social Sciences were used to analyze the data. Results: The ACU group(Exam A) reported fullness, heaviness, numbness, soreness and throbbing of significantly greater intensity than the NAP group(Exam B). In addition, there was no statistical significance between two groups in aching, tingling, deep pressure, sharp pain, dull pain, warmness and cold. Meanwhile, f MRI data revealed differences between two groups in discriminating accuracy of brain somatosensory cortex and language-related cortices. Conclusion: Needling HT 5 and GB 39 may modulate language function through a complex brain network, suggesting that it may be beneficial to the recovery of language function in patients with aphasia.Objective: To explore the specificity of Tongli(HT 5) and Xuanzhong(GB 39) paired acupionts in aspects of Deqi sensation and brain activation patterns during electroacupuncture. Methods: In this study, 15 healthy subjects were enrolled. All participants suffered two kinds of functional magnetic resonance imaging(f MRI) examinations randomly: Examination A received electro-acupuncture(EA) at the bilateral Tongli(HT5) and Xuanzhong(GB 39) acupoints(ACU), and examination B received EA at bilateral non-acupoints(NAP). The subjects reported the feeling of Deqi at each examination later respectively. A multi-voxel pattern analysis method and Statistical Program for Social Sciences were used to analyze the data. Results: The ACU group(Exam A) reported fullness, heaviness, numbness, soreness and throbbing of significantly greater intensity than the NAP group(Exam B). In addition, there was no statistical significance between two groups in aching, tingling, deep pressure, sharp pain, dull pain, warmness and cold. Meanwhile, f MRI data revealed differences between two groups in discriminating accuracy of brain somatosensory cortex and language-related cortices. Conclusion: Needling HT 5 and GB 39 may modulate language function through a complex brain network, suggesting that it may be beneficial to the recovery of language function in patients with aphasia.

关 键 词：electroacupuncture Tongli(HT 5) Xuanzhong(GB 39) functional magnetic resonance imaging brain network 

分 类 号：R246[医药卫生—针灸推拿学]