平均血小板质量与降钙素原在儿童川崎病诊断中的应用价值  

Clinical Value of Mean Platelet Mass and the Procalcitonin in Diagnosis of Kawasaki Disease

作　　者：邓永超[1] 唐喜春[1] 杨娟[1] 黄彩芝[1] 莫丽亚[1] 

机构地区：[1]湖南省儿童医院检验科

出　　处：《现代检验医学杂志》2016年第5期144-146,共3页Journal of Modern Laboratory Medicine

摘　　要：目的：探讨平均血小板质量（mean platelet mass，MPM）与降钙素原（procalcitonin，PCT）在儿童川崎病（kawasaki disease，KD）诊断中的应用价值。方法分别测定117例急性期川崎病患儿的 MPM与血小板计数（PLT）、平均血小板体积（MPV）、血小板体积分布宽度（PDW）以及降钙素原（PCT）的水平，且与126例正常对照组儿童进行比较，并同时比较各指标的阳性率及相关性。结果①川崎病儿童急性期 MPM水平显著低于对照组，PLT，MPV及 PCT水平显著高于对照组（P＜0.05，α＝0.05）；两组PDW水平比较差异无统计学意义（P＞0.05，α＝0.05）。②MPM阳性率明显高于其它指标（P＜0.05，α＝0.05）。结论 MPM对儿童川崎病诊断具有较好的应用价值，可作为一项实验室辅助诊断指标在临床推广。Abstact：Objective To investigate the clinical value of mean platelet mass（MPM）and the procalcitonin（PCT）in diagnosis of Kawasaki disease （KD）.Methods A Total of 117 children with KD in the acute stage and 126 children of the control group were detected respectively and compared each other.The indexes contain MPM,PLT,MPV,PDW and PCT.Mean-while,the comparison of each index’s positive rate and the linear correlation analysis of each index were conducted.Results①The level of MPM of the KD group was significant lower than that of the control group,PLT,MPV and PCT significant higher than those （P〈0.05,α=0.05）.The difference of PDW between the two groups was no statistical significance （P〉0.05,α=0.05）.②The positive rate of the MPM was significant higher than that of the other indexes （P〈0.05,α=0.05）. Conclusion The detection of MPM is helpful to the diagnosis of KD and can be used as an indicator of KD clinically.

关 键 词：平均血小板质量 川崎病 儿童 

分 类 号：R55[医药卫生—血液循环系统疾病] R446.11[医药卫生—内科学]