儿童眼部肿瘤504例临床病理学分析  

Clinical and pathological analysis of ocular tumors in 504 children cases

作　　者：赵云[1] 赵红[1] 林锦镛[1] 潘叶[1] 翟文娟[1] 王玉川[1] 

机构地区：[1]天津市眼科医院天津医科大学眼科临床学院天津市眼科学与视觉科学重点实验室天津市眼科研究所,300020

出　　处：《中华眼科杂志》2016年第10期764-768,共5页Chinese Journal of Ophthalmology

摘　　要：目的 分析儿童眼部肿瘤的临床病理学特点.方法 回顾性系列病例研究.收集2002年1月至2014年12月在天津市眼科医院存档,并经手术治疗后病理检查确诊的504例（506只眼）眼部肿瘤患儿的临床资料.分析肿瘤的发生部位、临床特点及病理分型.结果 504例儿童眼部肿瘤患儿中,男性246例（248只眼）,女性258例（258只眼）.患儿就诊年龄为4个月至14岁,平均年龄为6.4岁.眼睑和眼表肿瘤328例（330只眼）,占65.1％,其中恶性肿瘤2例（0.6％）,其余均为良性肿瘤,位居前4位的是角膜皮样瘤、皮样囊肿、色素痣和毛母质瘤;眼眶肿瘤123例（123只眼）,占24.4％,其中恶性肿瘤13例（10.6％）,其余均为良性肿瘤,前4位依次为皮样囊肿、淋巴管瘤、血管淋巴管瘤和静脉性血管瘤;而在眼内肿瘤53例（53只眼,10.5％）中,恶性肿瘤41例（77.4％）,均为视网膜母细胞瘤.结论 儿童眼部肿瘤以先天性和胚胎性肿瘤为主,其中以眼睑和眼表肿瘤最多见.良性肿瘤以角膜皮样瘤、皮样囊肿多见,恶性肿瘤主要为视网膜母细胞瘤、横纹肌肉瘤等.Objective To analyze the clinical features and pathological classification of chlidren＆#39;s ocular tumors.Methods Retrospective case series study.Five hundred and four cases （506 eyes） of ocular tumor with biopsy-proven in children below 14 years old between January 2002 and December 2014 from Tianjin Eye Hospital were performed to retrospectively investigated the lesion location,clinical features and histopathologic classification of these lesions.Results Of 504 cases there were 246 boys （248 eyes） and 258 girls （258 eyes） patients.The mean age at diagnosis was 6.4 years,ranged from 4 months to 14 years.Of 328 cases （65.1%） of eyelid and ocular surface,2 cases （0.6%） were malignant tumors and other tumors were all benign tumors.The leading four tumors were corneal dermoid,dermoid cysts,nevus and pilomatricoma.Of 123 cases （24.4%） of orbital tumors,13 cases （10.6%） were malignant tumors and other tumors were all benign tumors.The leading four tumors were dermoid cysts,lymphangiomas,hemolymphangioma and venous hemangioma.Of 53 cases （10.5%） of intraocular tumors,41 cases （77.4%） were malignant tumors which were all retinoblastoma.Conclusions Most of children＆#39;s ocular tumors were congenital and embryonic tumors.The most common ocular tumors of 504 children patients were from eyelid and ocular surface.Corneal dermoid and dermoid cysts were the most benign ones.Retinoblastoma and rhabdomyosarcoma were the most malignant ones.

关 键 词：眼肿瘤 皮样囊肿 视网膜母细胞瘤 横纹肌肉瘤 儿童 

分 类 号：R739.7[医药卫生—肿瘤]