左心辅助装置表层氧化钛薄膜与血液相容性的研究进展  

Research progress of surface titanium oxide film of LVAD and its blood compatibility

作　　者：田琨[1,2] 武亚东 梁法禹[3] 

机构地区：[1]河北北方学院,河北张家口075000 [2]河北省邯郸市中心医院东区神经内科,河北邯郸056000 [3]山西医科大学第一医院心胸外科,山西太原030001

出　　处：《中国现代医生》2016年第27期163-165,168,共4页China Modern Doctor

基　　金：山西省科技攻关项目(20090311057-11)

摘　　要：钛及钛合金,由于其表面自然形成了一层薄的氧化钛膜,因而具有较好的血液相容性。钛合金制备的左心辅助装置对挽救心力衰竭患者生命有十分重要的作用。本文简述了生物材料表面形成血栓的机制,并综述了氧化钛薄膜的研究进展及应用现状,同时对生物材料的前景进行了展望。分析表明钛及其合金具有良好的生物相容性主要归功于表面附着的氧化层。Titanium and titanium alloy have favorable blood compatibility because of a layer of thin titanium oxide film formed on its surface. The LVAD prepared by titanium alloy plays an important role in rescuing the life of the patients with heart failure. The article briefly introduces the mechanism of formation of thrombus on the surface of biological materials, and also summarizes the research progress and current situation of application of titanium oxide film. It also makes expectations on the prospect of biological materials. Analysis demonstrates that titanium and its alloy have favorable biological compatibility, owing to the oxidation layer on the surface.

关 键 词：氧化钛薄膜 血液形容性 血栓 生物材料 钛合金 

分 类 号：R318.08[医药卫生—生物医学工程]