正确认识血小板功能检测在急性冠状动脉综合征患者抗血小板治疗中的价值  

Deciphering the platelet function test inacute coronary syndrome patients subjected to anti-platelet therapy

作　　者：张真路[1] 张李涛[1] 

机构地区：[1]武汉亚洲心脏病医院武汉大学附属心脏病医院检验医学中心,430022

出　　处：《中华检验医学杂志》2016年第10期743-746,共4页Chinese Journal of Laboratory Medicine

摘　　要：抗血小板治疗是急性冠脉综合征（ACS）治疗的基石，血小板功能检测可以评估抗血小板治疗的效果，而关于血小板功能检测是否能用于指导ACS抗血小板治疗依然存在争论。另外血小板功能检测的方法众多，常见用于抗血小板治疗监测的检测方法各有优缺点。根据近年循证资料、指南共识和临床经验，对ACS疾病中，血小板功能检测的目标人群、药物、检测方法、质量保证及结果解释进行综述，希望能有助于检验人员和临床医生正确理解血小板功能检测在ACS患者抗血小板治疗中的意义。Anti-platelet therapy plays a key role in acute coronary syndrome （ACS） treatments Platelet function tests could monitor the effect of anti-platelet drugs＇, however, it is still under debate that whether platelet function monitoring could be used to adjust antiplatelet therapy. Additionally, there are a number of platelet function assays, and each of them has specifically advantages and disadvantages, This article reviewed evidence-based information, guidelines, consensus and clinical experience about platelet function monitoring in ACS patients, which was intend to help laboratory technicians and clinicians understanding the value of platelet function tests in monitoring anti-platelet therapy.

关 键 词：急性冠脉综合征 血小板功能试验 血小板聚集抑制剂 

分 类 号：R541.4[医药卫生—心血管疾病]