超声极速成像技术评价代谢综合征颈动脉弹性的初步研究  

Preliminary Study of Evaluating Carotid Artery Elasticity in Metabolic Syndrome Using Ultrafast Imaging Technique

作　　者：韦宗凯 杨军[1] 杨茹[1] 刘皇亮 刘文[1] 张敏萍[1] 单忠艳[2] 赖亚新[2] 

机构地区：[1]中国医科大学附属第一医院心血管超声科,沈阳110001 [2]辽宁省内分泌疾病重点实验室,中国医科大学附属第一医院内分泌与代谢病科,沈阳110001

出　　处：《中国医科大学学报》2016年第11期988-991,共4页Journal of China Medical University

基　　金：“十一五”国家科技支撑计划(2009BAI80B00);辽宁省高等学校重大科技平台基金(16010)

摘　　要：目的探讨超声极速成像技术早期定量评价代谢综合征(MS)患者颈动脉弹性的临床应用价值。方法对沈阳市某社区健康体检人群行颈动脉超声检查,使用超声极速成像技术定量测量颈动脉脉搏波传导速度(PWV)[收缩期开始时PWV(PWVBS)和收缩期结束时PWV(PWVES)]。根据血液生化检查结果及体格检查结果分为MS组(A组),未达MS诊断标准组(B组)及完全正常组(C组)。结果 A组和B组的左侧颈动脉PWVBS及PWVES高于右侧(P均<0.05),而C组左、右侧颈动脉PWVBS及PWVES差异无统计学意义(P>0.05);A组及B组左侧颈动脉内膜中层厚度(IMT)、PWVBS和PWVES(L-IMT、LPWVBS和L-PWVES)均大于C组(P均<0.05);A组与B组比较L-PWVBS和L-PWVES差异均具有统计学意义(P均<0.05),但LIMT差异无统计学意义。结论 MS患者及未达MS诊断标准的患者颈动脉弹性均较正常人减低,且左侧减低要早于右侧,超声极速成像技术可早期评价MS患者及未达MS诊断标准患者颈动脉弹性的变化。Objective To explore the clinical application value of early quantitative evaluation of carotid artery elasticity using ultrafast imaging technique in patients with metabolic syndrome （MS）. Methods Carotid ultrasound examination was performed in health community residents of a community in Shenyang, and the pulse wave velocity （PWV） [ PWV at the beginning of the systole （ PWVBS ） and the PWV at the ending of the systole （PWVES） 1 of carotid artery was measured using ultrafast imaging technique. According to the results of blood biochemical examination and physical examination results, all subjects were divided into MS group （group A）, group of patients who haven＇ t reached the diagnostic standard of MS （group B） and completely normal group （group C ）. Results PWVBS and PWVES of left carotid artery of group A and B were higher than the right side （P 〈 0.05 ）, while no significant difference was observed between the left and right carotid arteries in group C ; PWVES, PWVBS and intima-media thickness （IMT） of left carotid artery （L-PWVBS, L-PWVES and L-IMT） of group A and group B were higher than those of group C （P 〈 0.05 ） ; There were significant differences in both L-PWVBS and L-PWVES between group C and group B （ P 〈 0.05 ）, but no signifi- cant difference was found in L-IMT. Conclusion The carotid artery elasticity in patients with MS and patients who haven＇ t reached the diagnos- tic standard of MS is lower; in addition, it happens earlier in the left carotid artery. Furthermore, early evaluation of carotid artery elasticity in pa- tients with MS and patients who haven＇ t reached the diagnostic standard of MS can be made by ultra_fast imaging technique.

关 键 词：代谢综合征 颈动脉弹性 脉搏波传导速度 超声极速成像技术 

分 类 号：R589[医药卫生—内分泌]