血小板/淋巴细胞比值和2型糖尿病微血管病的相关性  

Correlation between platelet to lymphocyte ratio and microangiopathyin type 2 diabetes mellitus

作　　者：刘光辉[1] 方萍[1] 赵家胜[1] 

机构地区：[1]同济大学附属同济医院内分泌代谢科,上海市200065

出　　处：《实用医学杂志》2016年第20期3306-3309,共4页The Journal of Practical Medicine

摘　　要：目的：探究外周血血小板与淋巴细胞比值（PLR）和2型糖尿病微血管病相关性。方法：回顾性分析2009年12月至2015年12月我院的2型糖尿病肾病患者428例患者的临床资料,分析外周血血小板与淋巴细胞比值、年龄、性别、空腹血糖、糖化血红蛋白、总胆固醇、甘油三酯等指标和2型糖尿病微血管病的相关性。结果：Logistic回归分析显示PLR是2型糖尿病微血管病的危险因素（OR=3.162,95%CI：1.556～7.421,P〈0.05）。结论：PLR是2型糖尿病微血管病的危险因素,临床工作中应重视PLR异常变化的2型糖尿病患者。Objective To explore the relationship between platelet to lymphocyte ratio（PLR） and microangiopathyin type 2 diabetes mellitus. Methods In this case-control study, the clinical data on 428 adult patients with type 2 diabetic microangiopathy in our hospital from January 2009 to December 2015 were retrospectively analyzed. PLR, age, sex, fasting blood glucose, glycosylated hemoglobin, total cholesterol and triglyceride were tested to investigate their relationship with type 2 diabetic microangiopathy. Results Logistic regression analysis showed that PLR was a risk factor of type 2 diabetic microangiopathy（OR = 3.162, 95%CI：1.556 ～ 7.421, P〈0.05）. Conclusions Greater PLR is closely related to type 2 diabetic microangiopathy,and we should pay attention to type 2 diabetic microangiopathy with a greater PLR in clinical practice.

关 键 词：血小板与淋巴细胞比值 2型糖尿病微血管病 相关性 

分 类 号：R587.2[医药卫生—内分泌]