冠状动脉病变程度与抑郁障碍相关性研究  

Relationship between the severity of coronary artery stenosis and depression

作　　者：马颖艳[1] 关绍义[1] 杨桂棠[1] 刘亚斌[1] 李娜[1] 刘韵情 韩雅玲[1] 

机构地区：[1]沈阳军区总医院心血管内科,辽宁沈阳110016

出　　处：《临床军医杂志》2016年第5期477-479,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨胸痛患者冠状动脉病变程度与抑郁障碍的关系。方法选取2014年10月至2015年6月收治的717例胸痛患者,行冠状动脉造影术前采用综合医院抑郁量表(HADS-D)进行测评,统计抑郁症的发病率。同时,结合Gensini评分标准对患者冠状动脉病变进行分级,分析冠状动脉病变程度与HADS-D评分的关系。结果本组717例患者中,235例患抑郁症,发病率为32.78%。冠状动脉正常者及冠心病患者抑郁症发病率分别为40.83%(49/120)和31.16%(186/597),差异有统计学意义(P<0.05)。冠状动脉正常者及冠状动脉重度狭窄患者抑郁评分分别为(6.38±3.80)分和(6.82±3.93)分,较其他程度冠状动脉病变患者高。不同程度冠状动脉病变患者抑郁症发病率比较,差异有统计学意义(P<0.05)。结论冠状动脉正常及冠状动脉重度狭窄者更易出现抑郁障碍,抑郁障碍程度与冠状动脉病变程度无相关。Objective To explore the relationship between the severity of coronary artery stenosis and depression in patients with heart symptom. Methods Clinical data of 717 cases with chest pain were collected in The General Hospital of Shenyang Military Region from October 2014 to June 2015. Before coronary angiography, all the patients were evaluated by general hospital depression scale （HADS-D） and the incidence of depression were analyzed. Meanwhile the relationship between the SDS-D score and the Gensini coro- nary artery score were assessed. Results Among 717 cases of patients with heart symptom, 235 cases had depression, the incidence was 32. 78%. The incidence of depression in patients with normal coronary artery was 40. 83% （49/120）and in patients with coronary artery disease was 31.16% （ 186/597 ）. There was statistical significance, P 〈 0. 05. SDS-D score in the non-CHD group （6. 38 ± 3. 80）and in the serious coronary artery stenosis group（6. 82± 3.93 ）were higher than that in other patients with coronary artery le- sions. Incidence of depression in patients with different severities of coronary artery stenosis, the difference was statistically significant （P 〈 0. 05）. Conclusion There are high frequencies of depression in patients with non-CHD and in patients with serious artery ste- nosis. Depression is not obviously related to the severity of coronary artery stenosis.

关 键 词：冠状动脉病变 抑郁程度 冠状动脉造影术 

分 类 号：R541.4[医药卫生—心血管疾病]