冠状动脉病变患者严重程度与冠心病危险因素的相关性研究  

Association between severity of coronary artery disease and risk factors for coronary heart disease

作　　者：卢仁荣[1] 林美明[1] 余新[1] 郑元琦[1] 

机构地区：[1]福建医科大学附属三明市第一医院,福建三明365000

出　　处：《心血管病防治知识（学术版）》2016年第9期31-33,共3页Prevention and Treatment of Cardiovascular Disease

摘　　要：目的研究冠心病患者冠状动脉病变严重程度与冠心病危险因素的相关性。方法选取我院2011年2月至2014年6月608例冠心病患者为研究对象,进行冠心病危险因素与冠状动脉不同病变程度单因素相关分析和多危险因素与冠心病的Logistic回归分析。结果冠状动脉病变严重程度与2型糖尿病、高血压、吸烟、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)水平显著相关(P<0.05)。它们都是冠心病独立危险因素,其中2型糖尿病是最强的预测因子(r=0.973,P<0.01)。结论冠状动脉病变严重程度与2型糖尿病、高血压、吸烟以及LDL-C、TC水平呈正相关,在冠心病的防治上,积极控制危险因素可能有助于减轻冠状动脉病变程度,改善预后。Objective To investigate the association between the severity of coronary artery disease and risk factors for coronary heart disease. Methods A total of 608 patients with coronary heart disease who were treated in our hospital from February 2011 to June 2014 were enrolled as study subjects. Univariate and multivariate logistic regression analyses were performed for the risk factors for coronary heart disease and the severity of coronary artery disease. Results The severity of coronary artery disease was significantly correlated with type 2 diabetes, hypertension,smoking, low-density lipoprotein cholesterol（LDL-C） level, and total cholesterol（TC） level（P 0.05）. All of them were independent risk factors for coronary heart disease, and type 2 diabetes was the strongest predictor（r =0.973, P 0.01）.Conclusion The severity of coronary artery disease is positively correlated with type 2 diabetes, hypertension, smoking,LDL-C level, and TC level. In the prevention and treatment of coronary heart disease, active control of risk factors may help to reduce the severity of coronary artery disease and improve the prognosis.

关 键 词：冠状动脉病变 冠心病 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]