大动脉炎合并神经系统症状临床特点及预后分析  

Analysis for Clinical Features and Prognosis of Taksyasu Arteritis Combining Neurological Symptoms

作　　者：梁二鹏 杨丽睿[1] 张慧敏[1] 宋雷[1] 钱海燕[1] 邹玉宝[1] 马文君[1] 蒋雄京[1] 吴海英[1] 周宪梁[1] 蔡军[1] 惠汝太 郑德裕[1] 

机构地区：[1]北京协和医学院中国医学科学院国家心血管病中心阜外医院高血压诊治中心,北京市100037

出　　处：《中国循环杂志》2016年第10期997-1001,共5页Chinese Circulation Journal

摘　　要：目的：探讨大动脉炎合并神经系统症状的临床特点及预后情况。方法：回顾性分析我院2002-01至2013-10住院的大动脉炎合并神经系统症状274例患者临床特点、影像学资料及预后情况。结果：男女比例1：4.3,平均发病年龄（28.2±11.2）岁,最常见神经系统表现为头晕214例（78.1%）,最常见的分型为Ⅲ型（广泛型）112例（40.9%）,最常受累动脉为左锁骨下动脉147例（53.6%）。累及3~4支弓上动脉的患者77例（28.1%）。脑卒中患者中,缺血性卒中多见于锁骨下动脉及颈总动脉狭窄闭塞性病变,而出血性卒中患者多见于降腹主动脉和（或）肾动脉狭窄闭塞性病变。心力衰竭是最常见死亡原因,也是存活人群中最常见的心血管事件。结论：大动脉炎患者合并神经系统症状有多种表现,并与累及动脉数量及部位相关。Objective：To explore the clinical features and prognosis in patients with Takayasu arteritis（TA） combining neurological symptoms.Methods：We retrospectively studied 274 TA patients combining neurological symptoms who admitted to our hospital from 2002-01 to 2013-10 for their clinical and imaging features with prognosis.Results：The ratio of male to female was 1：4.3 and the mean age of disease onset was at（28.2±11.2） years.The most common neurological symptom was dizziness（214/274 cases,78.1%）,most frequent type was type III TA（112 cases,40.9%）,most common affected artery was left subclavian artery（147 cases,53.6%）,and there were 77 cases（28.1%） with（3-4） branches of the aortic arch involvement.For stroke conditions,ischemic stroke was more frequently observed in patients with steno-occlusive lesions in subclavian artery and common carotid artery,while hemorrhagic stroke was more frequently found in patients with steno-occlusive lesions in descending aorta,abdominal aorta and/or renal artery.Heart failure was the most common cause of death,it was also the most common cardiovascular event in surviving cohorts.Conclusion：TA patients could have many neurological symptoms,which were related to the number and site of artery involvement.

关 键 词：大动脉炎 神经系统 脑卒中 

分 类 号：R54[医药卫生—心血管疾病]