立构复合PL(D) LA-TMC无规共聚物的制备、结构与性能  

Preparation,Structure and Properties of PLLA-TMC/PDLA-TMC Stereocomplexes

作　　者：吴小蒙[1] 陈萧宇 石莉[1] 范仲勇[1] WU Xiaomeng CHEN Xiaoyu Shi LI FAN Zhongyong(Department of Materials Se/ence, Fudan University, Shanghai 200433, Chin)

机构地区：[1]复旦大学材料科学系,上海200433

出　　处：《高等学校化学学报》2016年第11期2101-2107,共7页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:51373041和51673046)资助~~

摘　　要：以辛酸亚锡为催化剂,通过开环聚合法制备了聚左旋乳酸-三亚甲基碳酸酯(PLLA-TMC)和聚右旋乳酸-三亚甲基碳酸酯(PDLA-TMC)无规共聚物.利用共聚物中PLLA/PDLA链段形成立构复合体,通过溶液浇注法制备了PLLA-TMC/PDLA-TMC立构复合聚乳酸材料(sc-PLA-TMC).研究结果表明,聚合物链中的柔性TMC单元可以增强L(D)LA链段的运动能力,有助于不同旋光性的LA链段形成立构复合晶体,但也使得L(D)LA链段的规整度和序列长度降低.即随着共聚物链段中柔性TMC单元摩尔含量的增加,sc-PLA-TMC中同质结晶能力降低.当TMC含量≥5%时,仅生成熔点>200℃的PLLA/PDLA立构复合结晶,表明sc-PLA-TMC的耐热性有所提高.蛋白酶K降解实验表明,PL(D)LA-TMC共聚物的降解速率不但比PLLA高,而且可通过共聚物中TMC含量进行调控.A series of copolymers with high molecular weight（ Mn 〉1 × 105） based on 1,3-trimethylene carbonate（ TMC） and L-lactide（ L-LA） or D-lactide（ D-LA） was synthesized by ring-opening polymerization using stannous octoate as catalyst. Then the stereocomplex sc-PLA films were prepared by mixing equal amount of the corresponding PLLA-TMC and PDLA-TMC solution and followed by solution casting. The chemical structure,thermal properties and enzymatic degradation behavior of sc-PLA films were characterized respectively. The results show that crystallinity of homochiral crystals in sc-PLA-TMC samples decreases with the increase of TMC content. Only stereocomplex crystals exist in sc-PLA-TMC samples when TMC contents beyond 5%. The enzymatic degradation results show that the degradation rate of samples is accelerated when TMC unit is introduced.

关 键 词：聚乳酸 聚三亚甲基碳酸酯 立构复合 结晶 酶降解 

分 类 号：O631[理学—高分子化学]