骨组织工程的研究进展和面临的问题  

The Research Progress and Limitations of Bone Tissue Engineering

作　　者：周晓[1] 盛小伍[1] 曾勇[1] 

机构地区：[1]湖南省肿瘤医院,湖南省长沙市410013

出　　处：《组织工程与重建外科杂志》2016年第5期319-321,共3页Journal of Tissue Engineering and Reconstructive Surgery

基　　金：国家卫生计生委临床重点专科(肿瘤科)建设项目子项目

摘　　要：骨缺损修复的移植物按其来源,可分为自体骨、同种异体骨、异种骨等,均存在自身的局限性。组织工程技术有望产生和人体骨类似的骨组织,解决目前骨缺损治疗的局限性。我们针对骨组织工程,就其临床研究进展以及亟待解决的问题进行综述。[Summary] The graft for repairing bone grafts can be categorized as autografts, allografts, and xenografts. However, each type of donor tissue comes with its own set of limitations. Tissue engineering strategies have been applied as promising alternatives to produce bone constructs that mimic the structure of natural bone and solve the limitations of bone defect treatment. In this paper, the research progress of bone tissue engineering was reviewed, and the limitations of current bone tissue approaches were discussed.

关 键 词：组织工程 生长因子 支架 细胞外基质 

分 类 号：Q813.12[生物学—生物工程]