超声测量肝前脂肪厚度与颈动脉硬化的相关性  

Correlation analysis between prehepatic fat thickness and carotid atherosclerosis by ultrasonography

作　　者：杨虹[1] 刘轩[1] 

机构地区：[1]天津市公安医院物检科B超室,天津300042

出　　处：《中国城乡企业卫生》2016年第9期4-6,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的探讨肝前脂肪厚度与颈动脉粥样硬化的关系。方法选择健康体检者107例,应用彩色多普勒超声检测仪测定颈动脉内膜-中层厚度(c-IMT),根据颈动脉粥样硬化程度分为c-IMT正常组35例,c-IMT增厚组34例,颈动脉斑块组38例。检测并比较3组体检者的肝前脂肪厚度、体重指数(BMI)、腰围(WC)、腰臀比(WHR)及血糖、血脂、血压水平,分析肝前脂肪与c-IMT的关系;Binary-Logistic回归分析影响颈动脉硬化的因素。结果 c-IMT正常组高密度脂蛋白胆固醇(HDL-C)水平>c-IMT增厚组>颈动脉斑块组(P<0.05),c-IMT正常组肝前脂肪厚度<c-IMT增厚组<颈动脉斑块组(P<0.01);相关分析显示c-IMT与肝前脂肪厚度、TC、WC呈正相关差异有统计学意义(r分别为0.467、0.218、0.271,P<0.05),与HDL-C呈负相关,差异有统计学意义(r=-0.206,P<0.05);Binary Logistic回归分析示肝前脂肪厚度、HDL-C是c-IMT的独立危险因素。结论肝前脂肪厚度是c-IMT的独立危险因素,可作为颈动脉粥样硬化的早期预测指标。Objective To investigate the relationship of prehepatic fat thickness and carotid atherosclerosis. Methods A total of 107 healthy persons were collected to be studied. Their carotid intima-media thickness （IMT） was measured by Doppler ultrasonography. And according to the results of carotid artery atheroselerosis, the patients were divided into normal c-IMT group （n=35）, thickened c-IMT group （n= 34） and plague formation group （n=38）. Their serum prehepatic fat thickness, BMI, WC, WHR, blood glucose, blood lipid, blood pressure were compared among three group and their relationship with c-IMT were analyzed. Binary Logistic regression was used to screen risk factors for carotid atherosclerosis. Results The level of HDL-C in normal c-IMT group was higher than that in plague formation group, and in that thickened c-IMT group （P〈0.05）, while prehepatic fat thickness was lower in normal c-IMT group than in plague formation group and than thickened c-IMT group. The c-IMT grade was positively correlated with prehepatic fat thickness, TC and WC （r=0.467, 0.218, 0.271, P〈0.05）, but was negative correlated with HDL-C （r=-0.206, P〈0.05）. Further more, Binary Logistic regression analysis showed that prehepatic fat thickness and HDL-C were independent risk factors for c-IMT. Conclusion Prehepatic fat thickness was independent risk factors in judging the developments of arteriosclerosis.

关 键 词：超声检查 肝前脂肪厚度 颈动脉内膜中层厚度 动脉硬化 

分 类 号：R445.1[医药卫生—影像医学与核医学]