布鲁菌病的临床诊治分析  

Clinical diagnosis and treatment of brucellosis disease

作　　者：谢莹[1] 吴志勤[1] 辛海光[1] 徐文胜[1] 金瑞日 

机构地区：[1]第二军医大学长征医院感染科,上海200003

出　　处：《中国临床医学》2016年第4期505-507,共3页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨布鲁菌病的临床特点、治疗和转归,以提高临床对布鲁菌病认识。方法:回顾性分析第二军医大学长征医院2010—2015年收治的8例布鲁菌病患者的临床资料,总结临床诊治经验。结果:5例患者有明确的流行病学史,3例患者流行病学史不明。8例患者临床表现均有发热、乏力、多汗,其中5例除上述症状外分别伴有关节炎、睾丸炎、淋巴结肿大和游走性肌肉疼痛。8例患者中性粒细胞比例正常或偏低,血沉均升高,其中3例患者部分肝功能指标升高。8例患者经内科积极治疗后治愈,1例患者出院后继续饲养山羊后再发。结论:布鲁菌病临床表现多样,非疫区患者出现发热、乏力、多汗或关节肌肉疼痛等症状需警惕该病可能,并尽早给予规范的抗菌治疗。Objective： To analyze and review the epidemiology , clinical features , treatment and prognosis of brucellosis ,in order to raise awareness of brucellosis in clinic .Methods：Eight clinical cases of brucellosis in Changzheng Hospital from 2010‐2015 were analyzed retrospectively ,and the clinical treatment experiences were concluded .Results：Five patients had history of epidemic exposure ,the epidemic exposure history of 3 cases were unknown .All patients had fever , fatigue and hyperhidrosis ,which 5 cases were accompanied by arthritis ,orchitis ,lymphadenectasis ,or migratory myalgia .The percentages of neutrophils in 8 cases were normal or relatively low ,and the erythrocyte sedimentation rate （ESR） was elevated in all patients ,in addition ,some indexes of liver function were elevated in 3 cases .All patients were cured by anti‐infective therapy , one patient who re‐contacted with goat was recrudescence .Conclusions： Brucellosis shows various clinical manifestations .Patients in non‐epidemic areas who have long‐term fever ,fatigue ,sweating or joint and muscle pain should be guarded against brucellosis ,and provide patients with early diagnosis and anti‐infective therapy .

关 键 词：布鲁菌病 临床特征 回顾性分析 

分 类 号：R378.5[医药卫生—病原生物学]