胃黏膜中幽门螺杆菌形态对胃黏膜病理性特征影响分析  

Pathological characteristics of gastric mucosa infections due to helicobacter pylori

作　　者：甘昌志 李荷花[2] 符诗勤 

机构地区：[1]台州市中医院病理科,浙江台州318000 [2]浙江省台州医院手术室,浙江临海317000 [3]台州市中医院消化内科,浙江台州318000

出　　处：《中国中西医结合消化杂志》2016年第10期776-779,共4页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]考察胃黏膜中幽门螺杆菌(Hp)形态对胃炎病理性特征影响。[方法]回顾性分析400例行胃黏膜检查患者的临床资料,依据是否存在Hp感染分为感染组(237例)和未感染组(163例),并将感染组依据Hp形态将胃炎患者分为单纯球形组(62例)和伴螺旋状组(175例)。比较2组患者病理性形态差异,并用统计学软件进行分析。[结果]2组患者性别、炎症类型和严重程度比较差异有统计学意义(P<0.05)。单纯球形组患者女性比例显著高于伴螺旋状组(P<0.05)。单纯感染组患者炎症活动率和间质淋巴细胞数量差异有统计学意义(P<0.05)。[结论]Hp对胃黏膜具有致病性,且男性患者感染患有更高危害的螺旋状幽门杆菌概率更高。[Objective]To investigate the effect of the morphology of Helicobacter pylori（HP）in the gastric mucosa on the pathological characteristics of gastritis.[Methods]A retrospective analysis of clinical data of 400 gastritis patients who underwent gastric mucosa biopsy was performed.According to the existence of HP infection,the patients were divided into infection group（237cases）and non-infection group（163cases）,and the infected group were further divided into simple spherical group（62cases）and spiral and spherical group（175 cases）.The pathological morphological differences were compared between different groups,and the statistical software was used to analyze the differences.[Results]There was significant difference in the gender,the type of inflammation and the severity between the infection group and the noninfection group（P〈0.05）.The proportion of female patients in simple spherical group was significantly higher than that of spiral and spherical group（P〈0.05）.There was statistical significance in the rate of inflammatory activity and the number of lymphocytes in the patients of simple infection group（P〈0.05）.[Conclusion]Helicobacter pylori is highly pathogenic to gastric mucosa,and the risk of spiral Helicobacter pylori infection is higher in male patients with higher harm.

关 键 词：胃炎 幽门螺杆菌 感染 病理学 

分 类 号：R573.6[医药卫生—消化系统]