非层状液晶在经皮传递系统中的应用概述  

Application of Non-lamellar Liquid Crystals in Transdermal Delivery Systems

作　　者：陈博[1,2,3] 纪宏宇[1,2,3] 孙玉阳[1,2,3] 初明慧 王海荣[4,2,3] 吴琳华[1,2,3] 

机构地区：[1]哈尔滨医科大学附属第二医院药学部,哈尔滨150086 [2]哈尔滨医科大学药学院 [3]黑龙江省高校重点实验室 [4]哈尔滨医科大学附属第二医院学部,哈尔滨150086

出　　处：《中国药师》2016年第11期2138-2141,共4页China Pharmacist

摘　　要：目的:综述非层状液晶作为药物载体在经皮传递系统中的应用进展。方法:根据国内外发表的最新文献,对非层状液晶在经皮传递系统中的作用机制以及应用进行分析与讨论。结果:非层状液晶作为药物载体在经皮传递系统的应用越来越广泛,该载体具有增溶、包封、保护药物;促进药物渗透;提高载药量;提高药物的稳定性等作用。结论:非层状液晶作为药物经皮传递载体在医药卫生等领域具有较好的发展前景。Objective： To review the application of non-lamellar liquid crystals as vehicles in transdermal delivery systems. Methods： Based on the recently published papers, the application researches of non-lamellar liquid crystals in transdermal delivery systems were classified and summarized. Results： Non-lamellar liquid Crystals were extensively applied as drug vehicles due to the ability of solubilization, encapsulation, protection, drug penetration enhancement, drug-loading improvement and stabilization. Conclusion： Non-lamellar liquid crystals as promising vehicles used in medicine and health care filed show good application prospect.

关 键 词：非层状液晶 载体 经皮传递系统 应用 

分 类 号：R945[医药卫生—微生物与生化药学]