基于偏定向相干性的体感振动脑网络研究  

Brain Network Research under Somatosensory Vibration Stimulation Based on Partial Directed Coherence

作　　者：马娜[1] 王学民[1,2] 田苗[1] 刘静[1] 綦宏志[1,2] 明东[1,2] 周鹏[1,2] Ma Na Wang Xuemin Tian Miao Liu Jing Qi Hongzhi Ming Dong Zhou Peng(School of Precision Instrument and Optoelec- tronics Engineering, Tianjin University, Tianjin 300072, Chin)

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072 [2]天津市生物医学检测技术与仪器重点实验室,天津300072

出　　处：《航天医学与医学工程》2016年第5期334-338,共5页Space Medicine & Medical Engineering

基　　金：国家自然科学基金项目(51377120;51007063;31271062;81222021;61172008;81171423);天津市自然基金项目(13JCQNJC13900);国家科技支撑计划项目(2012BAI34B02);教育部新世纪优秀人才支持计划项目(NCET-10-0618)

摘　　要：目的探究20 Hz体感振动作用对大脑功能状态调节机制的影响规律。方法对12名20-25岁志愿者（6男6女）进行了20 Hz体感振动刺激实验,采集了志愿者振动前和停振后短时及长时效应期间脑电信号,采用基于偏定向相干性（partial directed coherence,PDC）的方法构建了脑拓扑网络,比较分析了刺激前后网络参数（节点度、集群系数）变化。结果振动后,节点入度相对节点出度分布更为集中;大脑左右半球对20 Hz体感振动具有不同的响应,显示出右侧出、入度优势;集群系数减小。结论由脑网络信息流及网络参数的变化得知,20 Hz体感振动刺激能够改变脑网络连接方式及运行效率,从而调节大脑功能状态。Objective To study the regulation mechanism of brain function induced by 20 Hz somatosensory vibration. Methods Twelve subjects（ six males and six females） aged from 20 to 25 years old were involved in20 Hz vibration stimulation. EEG signal acquisition during short-term and long-term effects was conducted,and partial directed coherence（ PDC） was applied to construct a brain network of which parameters were analyzed,such asthenode degree and cluster coefficient. Results Distribution of the in-degree of nodes was more concentrated than the out-degree of nodes; different cerebral hemisphere had different responses to 20 Hz frequency vibration,which showed the right side dominance on In-degree and Out-degree; cluster coefficient of the brain network was decreased. Conclusion The information flow difference and parameters results indicate that the connection mode and the operation efficiency of brain network can be altered by 20 Hz vibration,thus to regulate the state of the brain function.

关 键 词：体感振动 脑网络 偏定向相干性 

分 类 号：R318[医药卫生—生物医学工程] R857[医药卫生—基础医学]