新生儿脓毒症危重病例评分与血小板数量关系探讨  

The relationship between the platelet count and the severity of neonatal sepsis

作　　者：魏恩焕[1] 杨惠[1] 黄建明[1] 

机构地区：[1]福建医科大学附属三明第一医院NICU,福建福州365000

出　　处：《实用医院临床杂志》2016年第6期63-65,共3页Practical Journal of Clinical Medicine

摘　　要：目的探讨外周静脉血血小板数量在不同脓毒症新生儿危重病例评分的变化情况。方法 2013年1月至2015年12月我院儿科收治106例新生儿脓毒症患儿,根据确诊为新生儿脓毒症后24 h内危重病例评分法分为非危重组56例、危重组28例和极危重组22例,3组均在确诊为新生儿脓毒症后24 h内采集静脉血测定血小板,对3组患儿静脉血血小板数量和人数分布进行比较。结果危重组静脉血血小板数量高于非危重组,显著高于极危重组,差异有统计学意义(P<0.01);危重组血小板增高(>300×109/L)占67.8%(19/28),极危重组血小板降低(<100×109/L)占68.1%(15/22)。结论脓毒症新生儿危重组血小板数升高,极危重组血小板数明显降低,监测血小板的变化对判断病情和估计预后有一定帮助。Objective To investigate the changes of peripheral venous blood platelet count in the different severities of neo-natal sepsis.Methods From Jan.2013 to Dec.2015,we treated 106 infants with sepsis.The infants were divided into three groups ac-cording to the score of critical illness within 24 h after diagnosis of neonatal sepsis：non critical group （n =56）,critical group （n =28） and extremely critical group （n =22）.The number of peripheral blood platelets among the three groups was compared.Results The venous blood platelet count in the critical group was higher than that in the non critical group （ P〈0.05） and the extremely criti-cal group （P 〈0.01）.The incidence of increased platelet count （〉300 x 109/L） in the critical group was 67.8%（19/28）.The in-cidence of decreased platelet count （〈100 x 109/L） in the extremely critical group was 68.1%（15/22）.Conclusion The number of platelet in the critical group is significantly increased while the number of platelet in the extremely critical group is obviously de-creased.Therefore,monitoring the changes of platelet is helpful to estimate the condition and the prognosis.

关 键 词：新生儿 败血症 危重病例评分 血小板 

分 类 号：R446.11[医药卫生—诊断学]