湖北省13种危险因素的疾病负担研究  

Estimation on the Disease Burden Attributable to 13 Risk Factors in Hubei Province

作　　者：崔芳芳[1,2] 张岚[3] 宇传华[1,2] 潘敬菊[3] 

机构地区：[1]武汉大学公共卫生学院流行病与卫生统计学系,430072 [2]武汉大学全球健康研究中心 [3]湖北省疾病预防控制中心慢病所

出　　处：《中国卫生统计》2016年第5期778-781,784,共5页Chinese Journal of Health Statistics

基　　金：湖北省自然科学基金(2015CFB589);国家自然科学基金(81273179);湖北省卫计委科研基金(JX6B22)

摘　　要：目的分析湖北省主要危险因素所致疾病负担。方法根据2010年湖北省慢性病及其危险因素监测获得主要危险因素人群暴露率,结合文献采用反事实分析法计算人群归因分值(PAF),然后根据全球疾病负担(GBD)2013的研究获得疾病的伤残调整寿命年(DALY),结合PAF计算危险因素归因死亡和归因DALY。结果湖北省人群54.24%的死亡和34.32%的DALY由纳入研究的13种危险因素所致,其中高血压、吸烟、高BMI指数、水果摄入不足、饮酒是导致死亡的前五位危险因素,分别导致14.25%、12.24%、5.83%、3.98%和3.27%的死亡,归因DALY的前五位危险因素及归因比例分别为:高血压(8.81%)、吸烟(6.68%)、高BMI指数(3.74%)、饮酒(2.82%)、水果摄入不足(2.25%)。结论危险因素所致疾病负担已严重影响人群生命质量,尤其是高血压、吸烟、高BMI指数和饮酒,进行危险因素干预可有效降低心脑血管疾病和恶性肿瘤等慢性病的死亡率,从而改善人群健康。Objective To analyze the disease burden attributable to main risk factors in Hubei province. Methods It can obtain the main risk factors for population exposure rate from the monitoring of chronic disease and its risk factors 2010 in Hubei Province, combined with literature,using counterfactual attribution method to calculate the population attributable fraction （PAF）. Deaths and DALYs attributed to the selected risk factors were than estimated together with disability-adjusted life years （DALY） from GBD 2013 study. Results 54. 24% of the total death and 34. 32% of the total DALYs from Hubei population were resulted from the 13 selected risk factors. The top five risk factors for death were ：high blood pressure, smoking ,high body- mass index,diet low in fruits and alcohol use,causing death of 14. 25% 、12.24% 、5.83% 、3.98% and 3.27% respectively. The top five risk factors for DALY were high blood pressure （8.81% ）, smoking （6. 68 % ）, high body-mass index （3.74%）, alcohol use（2. 82% ） and diet low in fruits（2. 25% ）. Conclusion The disease burden attributable to risk factors has influenced the quanlity of life severely, especially high blood pressure, smoking, high body-mass index and alcohol use. The mortality of chronic disease can be reduced if these risk factors were effectively under control, then the quanlity of life can be improved.

关 键 词：危险因素 疾病负担 死亡 伤残调整寿命年 

分 类 号：R195.4[医药卫生—卫生统计学]