粘叶莸的化学成分研究  

Chemical Components from Caryoptesis glutinosa

作　　者：罗国勇 郎天琼 周敏[2] 刘燕[2] 罗应刚[2] 张国林[2] 

机构地区：[1]贵阳中医学院药学院,贵阳550025 [2]中国科学院成都生物研究所,成都610041

出　　处：《天然产物研究与开发》2016年第10期1520-1525,共6页Natural Product Research and Development

摘　　要：综合利用多种色谱方法从粘叶莸(Caryopteris glutinosa)的乙醇提取物中分离得到13个化合物,并通过多种波谱学手段鉴定它们的结构分别为:caryopterpene J(1)、5-羟基-7,3',4'-三甲氧基黄酮(2)、5-羟基-7,8,4'-三甲氧基黄酮(3)、5-羟基-7,4'-二甲氧基黄酮(4)、8-甲氧基芹菜素(5)、5,4'-二羟基-7,8,3'-三甲氧基黄酮(6)、5,4'-二羟基-7,8-二甲氧基黄酮(7)、5-羟基-7,8,3',4'-四甲氧基黄酮(8)、acteoside(9)、N-trans-feruloyl 3-O-methyldopamine(10)、secoisolariciresinol(11)、isolariciresinol(12)和dehydroconiferyl alcohol(13)。其中,化合物1为新化合物,其它化合物除9以外均为首次从莸属植物中分离得到。Thirteen compounds were obtained from the ethanol extract of Caryopteris glutinosa by applying various chromatographic methods. Their structures were elucidated and identified as caryopterpene J （1）,5-hydroxy-7,3＇ ,4＇-trimethoxyflavone （ 2 ）, 5-hydroxy-7,8,4＇-trimethoxyflavone （ 3 ）, 5-hydroxy-7,4 ＇-dimethoxyflavone （ 4 ）, 8-methoxyapigenin （ 5）, 5,4＇-dihydroxy-7,8,3 ＇-trimethoxyflavone （ 6 ） , 5,4＇-dihydroxy-7,8-dimethoxyflavone （ 7 ） , 5-hydroxy-7,8,3＇, 4＇- tetramethoxyflavone （ 8）, acteoside （ 9）, N-trans-feruloyl-3-O-methyldopamine （ 10 ）, secoisolariciresinol （ 11 ）, isolarieiresinol （ 12 ） and dehydroconiferyl alcohol （ 13）, respectively, based on the spectral data, Among them, compound 1 was a new compound. The rest compounds excluding 9 were obtained from Caryopteris genus for the first time.

关 键 词：粘叶莸 环烯醚萜 木脂素 化学成分 马鞭草科 

分 类 号：R284.2[医药卫生—中药学]