江西省首例人感染H5N6禽流感死亡病例流行病学调查  

Human infection with avian influenza A(H5N6) virus in Jiangxi Province: first fatal case report

作　　者：刘晓青[1] 廖勇 谢春燕[3] 傅伟杰[1] 曾志笠 袁辉[1] 

机构地区：[1]江西省疾病预防控制中心应急办与传防所,江西南昌330029 [2]赣州市疾病预防控中心传染病防制科,江西赣州341000 [3]南昌大学江西医学院流行病与统计学教研室,江西南昌330006

出　　处：《中华疾病控制杂志》2016年第9期910-912,917,共4页Chinese Journal of Disease Control & Prevention

摘　　要：目的分析江西省首例人感染H5N6禽流感死亡病例流行病学特征,为防控人感染禽流感提供科学依据。方法采用描述性流行病学方法分析人感染H5N6禽流感病例诊疗和密切接触者信息,对感染来源进行现场流行病学调查,并采集生物和环境标本进行实验室检测。结果病例确诊为人感染H5N6禽流感,因呼吸衰竭死亡,密切接触者未发生H5N6禽流感传播;病例有活禽市场和家禽暴露史,工作处活禽销售摊档外1份环境标本H5亚型禽流感核酸阳性。结论江西省首例人感染H5N6禽流感死亡病例为异地感染,非人传人病例,感染来源可能与活禽市场暴露有关。Objective To analyze epidemiologieal characteristic of the first fatal H5N6 case in Jiangxi Province and provide scientific evidences for the disease control and prevention. Methods Epidemiologieal and clinical information of the case and close contacts were collected and analyzed by descriptive epidemiologic method. Field epidemiologieal in- vestigation including biological and environmental samples collecting were conducted, and then used for laboratory tests to figure out the infection source. Results This case was confirmed as human infection with avian influenza A （H5N6） virus and died from respiratory failure. There was no secondary case among the individuals＇ close contacts. There was a clear history of avian exposure for this case and H5 subtype nucleic acid was positive. Conclusions The first fatal H5 N6 case in Jiangxi Province was not local infection and there was no evidence suggesting human-to-human transmission. The source of infection may relate to contact with poultry in live poultry market.

关 键 词：禽流感 感染 流行病学方法 

分 类 号：R181.22[医药卫生—流行病学] R181.82[医药卫生—公共卫生与预防医学]