胱抑素C检测在老年人糖尿病肾病早期诊断中的意义  

The diagnosis effective of endogenous cystatin c( Cys C) in early renal injury of gerontal patients of type 2 diabetes mellitus

作　　者：杨瑞玲[1] 李丽燕[1] 赵旭东[1] 王春晴[1] 

机构地区：[1]徐州医学院附属医院老年科,江苏徐州221002

出　　处：《临床医药文献电子杂志》2016年第31期6131-6132,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的探讨胱抑素C水平在评价老年2型糖尿病肾病早期发现中的临床意义。方法糖尿病组:91例60岁以上的糖尿病患者(无高血压及慢性肾脏病病史,尿微量白蛋白<30 mg/dl;对照组:105例60岁以上的的无糖尿病、高血压及慢性肾脏病病史老年人。结果糖尿病组患者血尿素氮、肌酐水平与对照组患者血尿素氮、肌酐水平相比较,差异无统计学意义(P>0.05),糖尿病组患者血胱抑素水平明显高于对照组(P<0.05)。结论血胱抑素C测定有助于早期诊断老年糖尿病患者的糖尿病肾病。Objective To abserve the diagnosis effective of endogenous cystatin c （ Cys C） in early renal injury of gerontal patient with type 2 diabetes mellitus. Methods study group： gerontal patient of type 2 diabetes mellitus （91eases）without hypertension and chronic kidney disease （urinary albumin〈30 mg/dl） ; control group： gerontal patient people without type 2 diabetes meUitus 、 hyperten- sion and chronic kidney disease（105cases） ; the level of eystatinc （Cys C） 、 blood urea nitrogen（BUN） 、 serum ereatinine（ Scr ）were detected respectively. Results The level of the BUN and SCR has no differention between the control group and the study group. The level of Cys C concentration in study group is higher than that in control group. Conclusion the level of eyse concentration of gerontal patient with diabetes is meaningful for earlier diagnosis of diabetie nephropathy.

关 键 词：老年患者 2型糖尿病 胱抑素C 

分 类 号：R692.5[医药卫生—泌尿科学]