神经外科开颅术后颅内感染诊治新进展  

Latest progress of diagnosis and treatment of postoperative intracranial infection in neurosurgery department patients undergoing craniotomy

作　　者：邢永国[1] 孟伟英 张淑祥[1] 门树乐[1] 田晓静[1] 闫东明[2] 

机构地区：[1]天津中医药大学附属北辰中医医院神经外科,天津300400 [2]郑州大学第一附属医院神经外科,河南郑州450052

出　　处：《中华医院感染学杂志》2016年第22期5268-5271,共4页Chinese Journal of Nosocomiology

基　　金：河南省教育科学研究规划项目(2010-JKGHAG-058)

摘　　要：神经外科开颅手术后颅内感染是一种严重的神经外科并发症,可导致严重的后遗症,甚至危及患者的生命;最初当抗菌药用于临床预防术后感染时,开颅手术后颅内感染的发生率有一个明显下降的过程,但是随着抗菌药物的滥用,耐药菌株的增加,近年来其发生率又呈现上升的趋势;本综述简述了开颅术后颅内感染的临床特点、发病机制、病原菌、危险因素、诊断方法、治疗方法以及预后等,并提出开颅术后颅内感染的预防及及时诊断和治疗的建议。OBJECTIVE Postoperative intracranial infection in neurosurgery department patients undergoing craniot‐omy is a severe complication in department of neurosurgery ,which may lead to serious sequelae and even endan‐gers the lives of the patients .As antibiotics are initially used for clinical prevention of postoperative infection ,the incidence of the postoperative intracranial infection is remarkably decreased in the patients undergoing craniotomy ;however ,with the abuse of antibiotics and increase of drug‐resistant strains ,the incidence of the postoperative in‐tracranial infection then shows an upward trend .This review briefly describes the clinical characteristics of the postoperative intracranial infection ,pathogenesis ,pathogenic bacteria ,risk factors ,diagnosis approaches ,treat‐ment methods ,and prognosis ;the recommendations for prevention ,diagnosis ,and treatment of the postoperative intracranial infection are put forward for the patients undergoing craniotomy .

关 键 词：神经外科 开颅手术 颅内感染 脑脓肿 脑膜炎 

分 类 号：R651.11[医药卫生—外科学]