C_2～T_1三维有限元模型的建立和验证  

Establishment and verification of three-dimensional finite element model of C_2- T_1 vertebrae

作　　者：邓真[1] 王辉昊[1] 王宽[1] 兰天鹰 牛文鑫[1] 詹红生[1] 

机构地区：[1]上海中医药大学附属曙光医院,上海201203

出　　处：《中医正骨》2016年第10期1-6,共6页The Journal of Traditional Chinese Orthopedics and Traumatology

基　　金：国家自然科学基金项目(81473702;81503596);"中医骨伤科学"国家重点学科项目(100508);上海市中医药领军人才建设项目(2012-63-15);上海领军人才项目(041);"海派中医流派传承研究基地"项目(ZYSNXD-CC-HPGC-JD-001;ZY3-CCCX-1-1003);上海市中医药事业发展三年行动计划项目(ZYSNXD-CC-ZDYJ047)

摘　　要：目的：建立人体C2～T1三维有限元模型并进行验证。方法：采集1位健康男性志愿者的颈部CT图像，依次采用Mimics17．0医学图像处理软件、Geomagic12．0逆向工程软件及Abaqus 6．13有限元分析软件建立C2～T1三维有限元模型。约束T1下终板所有节点的全部6个自由度作为边界条件，在齿状突顶点上2mm处建立参考点，将其与C2齿状突所有单元节点耦合。对参考点分别施加±0．5Nm、±1Nm、±1．5Nm、±2Nm扭矩，模拟颈椎前屈、后伸、左右旋转、左右侧弯6种运动状态，计算不同条件下颈椎各节段活动度，与以往离体实验和有限元实验结果进行比较，同时观察各种运动状态下模型的应力分布情况。结果：建立的三维有限元模型模拟了C2～T1共7个椎体、6个椎间盘、5种韧带、6组关节软骨及上下终板，涉及60459个单元、128473个节点。模型在前屈、后伸、左右旋转、左右侧弯6种状态下的活动度与文献中的研究数据基本一致，应力分布与正常颈椎活动时的情况一致。结论：本研究建立的C2～T1三维有限元模型较为真实地模拟了正常颈椎的几何形态和材料属性，能够较为准确地反映正常颈椎的生物力学特性。Objective： To build and validate a three - dimensional finite element （FE） model of human C2 - T1 vertebrae. Methods： The neck CT image of one healthy male volunteer was collected,then the C2 - T1 three - dimensional FE model was built by using Mimics 17.0 medical image processing software, Geomagic 12.0 reverse engineering software and Abaqus 6.13 finite element analysis software in turn. Six degrees of freedom of all nodes in inferior endplate of T1 vertebrae were restrained and it was used as boundary condition. The reference point was built at 2 mm above the culminated point of odontoid process and was coupled with all unit nodes of C2 odontoid process. The torques （ ＋/- 0.5, ＋/- 1, ＋/- 1.5, and ＋/- 2 Nm, respectively） were applied to the reference point to simulate 6 kinds of motion of cervical vertebra, included anteflexion, backward extension, left - right rotation and left - right lateral flexion. The range of motion （ ROM ） of each segment of cervical vertebrae in different states of motion were calculated, and then the results were compared with those results of previous in vitro experiment and finite element experiment. Meanwhile, the stress distribution of the model in each state of motion was observed. Results：Seven vertebraes, six intervertebral disks, five kinds of ligaments and six groups of articular cartilage and endplates of C2 -TI were simulated by the three - dimensional FE model ,which included 60 459 units and 128 473 nodes. The ROM of the model in 6 kinds of states of motion, including anteflexion, backward extension, left -right rotation and left -right lateral flexion, were basically consistent with the lit- erature data. The stress distribution of the model was consistent with that of cervical spine in normal activities. Conclusion： The three di- mensional FE model of C2 - T1 vertebrae that we build in this study can literally simulate the geometric configuration and material attribute of normal cervical vertebrae and accurately reflect the biomechanieal char

关 键 词：颈椎 有限元分析 活动度 应力分布 

分 类 号：R681.55[医药卫生—骨科学]